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GRHL3 and GRHL2
Number of citations of the paper that reports this interaction (PubMedID
12549979
)
30
Data Source:
BioGRID
(two hybrid, pull down)
HPRD
(in vitro, two hybrid)
GRHL3
GRHL2
Description
grainyhead like transcription factor 3
grainyhead like transcription factor 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytosol
Cilium
Actin Cytoskeleton
Chromatin
Nucleus
Nucleoplasm
Cell-cell Junction
Membrane
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Chromatin DNA Binding
Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Intronic Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Chromatin DNA Binding
Identical Protein Binding
Sequence-specific DNA Binding
DNA-binding Transcription Factor Binding
Biological Process
Establishment Of Planar Polarity
Neural Tube Closure
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Pattern Specification Process
Ectoderm Development
Central Nervous System Development
Epidermis Development
Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Actin Cytoskeleton Organization
Wound Healing
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Eyelid Development In Camera-type Eye
Establishment Of Skin Barrier
Cochlea Morphogenesis
In Utero Embryonic Development
Neural Tube Closure
Cardiac Ventricle Morphogenesis
Epithelial Cell Morphogenesis
Regulation Of Transcription By RNA Polymerase II
Cell Adhesion
Brain Development
Epidermis Development
Regulation Of Gene Expression
Neural Tube Development
Keratinocyte Differentiation
Respiratory Tube Development
Cell Junction Assembly
Multicellular Organism Growth
Embryonic Digit Morphogenesis
Camera-type Eye Development
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Embryonic Organ Development
Embryonic Cranial Skeleton Morphogenesis
Face Development
Lung Lobe Morphogenesis
Lung Epithelial Cell Differentiation
Epithelial Cell Morphogenesis Involved In Placental Branching
Anterior Neural Tube Closure
Bicellular Tight Junction Assembly
Epithelium Migration
Pathways
Drugs
Diseases
GWAS
Cleft palate (
27018472
)
Fasting blood insulin (BMI interaction) (
22581228
)
Male-pattern baldness (
28196072
)
Response to interferon beta in multiple sclerosis (
26644207
)
Bronchopulmonary dysplasia (
23897914
)
Chronic hepatitis B infection vs asymptomatic persistence (
33736632
)
LDL levels x SSRI levels (escitalopram or citalopram) interaction in schizophrenia or bipolar disorder (
33824429
)
Rheumatoid arthritis (
24390342
30423114
)
Interacting Genes
8 interacting genes:
EAF1
ENKD1
GRHL1
GRHL2
PRMT1
PRMT5
PRMT6
RIPPLY1
6 interacting genes:
APP
GRHL3
LMO4
PAX5
PAX6
PIAS2
Entrez ID
57822
79977
HPRD ID
12210
10545
Ensembl ID
ENSG00000158055
ENSG00000083307
Uniprot IDs
Q8TE85
B4DL28
Q6ISB3
PDB IDs
5MR7
Enriched GO Terms of Interacting Partners
?
Histone H4R3 Methyltransferase Activity
Protein-arginine N-methyltransferase Activity
Histone Methyltransferase Activity
Histone Arginine N-methyltransferase Activity
Protein-arginine Omega-N Monomethyltransferase Activity
Peptidyl-arginine Methylation
Protein-arginine Omega-N Asymmetric Methyltransferase Activity
Methylosome
Regulation Of DNA-templated Transcription
Methyltransferase Activity
Regulation Of RNA Biosynthetic Process
Histone H3 Methyltransferase Activity
Methyl-CpG Binding
Regulation Of RNA Metabolic Process
Methylation
Protein Methylation
Regulation Of Megakaryocyte Differentiation
Regulation Of Nucleobase-containing Compound Metabolic Process
GATOR1 Complex Binding
Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway
Histone H2AR3 Methyltransferase Activity
Epithelium Migration
Regulation Of Gene Expression
Chromatin DNA Binding
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Peptidyl-arginine N-methylation
Histone H3R2 Methyltransferase Activity
Macromolecule Methylation
Protein-arginine Omega-N Symmetric Methyltransferase Activity
Regulation Of Signal Transduction By P53 Class Mediator
Epithelial Cell Morphogenesis Involved In Placental Branching
Intronic Transcription Regulatory Region Sequence-specific DNA Binding
N-methyltransferase Activity
Regulation Of Macromolecule Metabolic Process
Epidermis Development
Anterior Neural Tube Closure
Positive Regulation Of Hemoglobin Biosynthetic Process
Positive Regulation Of Dopamine Receptor Signaling Pathway
Somite Specification
Regulation Of Multicellular Organismal Development
Nucleoplasm
Chromatin Remodeling
Cellular Response To Methionine
Super Elongation Complex
Cell-cell Junction Organization
Regulation Of Hemoglobin Biosynthetic Process
Mitogen-activated Protein Kinase P38 Binding
Response To Methionine
Histone H4 Methyltransferase Activity
Central Nervous System Development
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
DNA-templated Transcription
Negative Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of RNA Metabolic Process
Positive Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Biosynthetic Process
Transcription By RNA Polymerase II
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Binding
System Development
Negative Regulation Of Macromolecule Biosynthetic Process
Chromatin
Negative Regulation Of Biosynthetic Process
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Response To Calcium Ion
Regulation Of MiRNA Transcription
Regulation Of MiRNA Metabolic Process
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Neuron Projection Development
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Embryonic Morphogenesis
Cerebral Cortex Development
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Forebrain-midbrain Boundary Formation
Chromatin DNA Binding
Pancreatic A Cell Development
Cell Fate Specification
Tube Closure
Neural Tube Closure
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Regulation Of Primary Metabolic Process
Negative Regulation Of Metabolic Process
RNA Metabolic Process
Acetylcholine Receptor Activator Activity
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Tagcloud (Difference)
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Tagcloud (Intersection)
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