PIH1D1 and TSC22D4

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		PIH1D1	TSC22D4
Gene Name		PIH1 domain containing 1	TSC22 domain family, member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-snoRNP Complex	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Box C/D SnoRNP Assembly Epithelial Cell Differentiation	Transcription, DNA-templated Response To Osmotic Stress Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CA4 FBL MAPK6 RBPMS RUVBL1 RUVBL2 TSC22D4	53 interactors: ABLIM1 AES AIFM1 APIP BLZF1 BZRAP1 CCDC146 CCDC33 CCDC42 CCNK CDC23 CDK5R1 CKS2 CLU ENKD1 FRMD6 FXR2 GNB2L1 GOLGA2 GORASP2 KEAP1 KPNA2 KRT40 LBP LMO2 LNX1 LRP2BP MAD2L1 MTHFS MYLIP NIF3L1 NOC4L NRBP1 NRBP2 PCBP1 PIH1D1 PIN1 POLR1C PPL PRKAA1 PRKAA2 PRNP PSMA1 SACS SAT1 SMAD3 SYT17 TEX11 TSC22D1 UBLCP1 ZBTB24 ZMYND10 ZNF580
Entrez ID		55011	81628
HPRD ID		07938	18231
Ensembl ID		ENSG00000104872	ENSG00000166925
Uniprot IDs		Q9NWS0	A8MWR6 Q9Y3Q8
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H2A Acetylation Histone H4 Acetylation Histone Modification DNA Duplex Unwinding DNA Geometric Change Histone Glutamine Methylation Histone Acetylation Internal Peptidyl-lysine Acetylation Chromatin Modification Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Peptidyl-glutamine Methylation Protein Acetylation RNA Metabolic Process Negative Regulation Of Estrogen Receptor Binding Transcriptional Activation By Promoter-enhancer Looping Chromatin Organization SnoRNA Metabolic Process Chromatin Remodeling Establishment Of Protein Localization To Chromatin DNA Recombination Negative Regulation Of Receptor Binding Peptidyl-lysine Modification Chromosome Organization Transcription, DNA-templated DNA Conformation Change Cellular Metabolic Process RNA Biosynthetic Process Protein Localization To Chromatin Nucleobase-containing Compound Metabolic Process Positive Regulation Of SMAD Protein Import Into Nucleus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of SMAD Protein Import Into Nucleus Cellular Response To Estradiol Stimulus Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Histone Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Response To Steroid Hormone CENP-A Containing Nucleosome Assembly Cellular Protein Modification Process Cellular Response To Estrogen Stimulus Protein Localization To Chromosome Nitrogen Compound Metabolic Process Bicarbonate Transport Histone Exchange DNA Replication-independent Nucleosome Assembly Gene Expression DNA Repair	Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Cell Cycle Negative Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Proteolysis Negative Regulation Of Cell Cycle Positive Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Cellular Process Cell Cycle Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cytokine Production Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Protein Ubiquitination Negative Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Positive Regulation Of Cell Death Regulation Of Protein Phosphorylation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cell Cycle Arrest Negative Regulation Of Signal Transduction Nitrogen Compound Metabolic Process Regulation Of Energy Homeostasis Negative Regulation Of Protein Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Glycolytic Process Cellular Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		atpases biochemistry chaperone ck2 client cochaperones connection connects consisting depends hsp90 mediates metazoa pi3 polymerases r2tp rpap3 rvb1 rvb2 simultaneously snornps spagh structural tah1 tel2 tti1 tti2 ttt	ablation cachectic cachexia clone deprivation diminished hepatic hepatocytes hypertriglyceridemia hypo hypobetalipoproteinemia lipids lipogenic livers mammals metabolic mimicking output proper rationale rescued secretion storage transforming triggers vldl wasting
Tagcloud (Difference) ?		atpases biochemistry chaperone ck2 client cochaperones connection connects consisting depends hsp90 mediates metazoa pi3 polymerases r2tp rpap3 rvb1 rvb2 simultaneously snornps spagh structural tah1 tel2 tti1 tti2 ttt	ablation cachectic cachexia clone deprivation diminished hepatic hepatocytes hypertriglyceridemia hypo hypobetalipoproteinemia lipids lipogenic livers mammals metabolic mimicking output proper rationale rescued secretion storage transforming triggers vldl wasting
Tagcloud (Intersection) ?