RBP5 and AGR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBP5	AGR2
Description		retinol binding protein 5	anterior gradient 2, protein disulphide isomerase family member
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Extracellular Region Extracellular Space Endoplasmic Reticulum
	Molecular Function	Retinoid Binding Fatty Acid Binding Protein Binding Lipid Binding Retinal Binding Retinol Binding	Dystroglycan Binding Epidermal Growth Factor Receptor Binding Protein Binding Identical Protein Binding
	Biological Process	Fatty Acid Transport	Inflammatory Response Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Response To Endoplasmic Reticulum Stress Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Digestive Tract Morphogenesis Positive Regulation Of Developmental Growth Lung Goblet Cell Differentiation Mucus Secretion Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of PERK-mediated Unfolded Protein Response
Pathways
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Refractive error ( 32231278)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Iron status biomarkers (ferritin levels) ( 28334935) Residual cognition ( 28441426) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Interacting Genes		5 interacting genes: ABCC5 AGR2 CCNDBP1 H3-4 NR0B2	87 interacting genes: ANKRD11 APOBEC3B APP ASPH BORCS8 BORCS8-MEF2B BRD7 C3 CAMLG CATSPER1 CCDC90B CD34 CD68 CDKN2AIPNL CETN3 CKAP2 CLIC3 CNNM3 CPNE6 CRCP CREB1 CRMP1 CRYGA CYB5R2 DAG1 DCAF11 EIF3F FABP2 FAM110A FAM117B GET3 GPSM2 GRB2 GUCA1A HCK HMG20A HSD3B7 IL36RN IMPDH2 KLHL38 KRT31 LSM1 LYPD3 MBD3 MBLAC1 MED31 MLH1 NDUFB2 NRF1 NRIP1 NSD1 NTAQ1 NUP54 NUP58 NUP62CL OSTF1 PHC3 POGZ POLR2L POM121 PSMA1 PSMB1 PSORS1C2 PTTG2 RBFOX1 RBP5 RIIAD1 RTL4 RUVBL2 SDC3 SGTA SGTB SH2D1B STK16 TCEA2 TFAP2D THOC1 TLE5 TMEM123 TRAF2 TSTD2 UBE2I UBQLN1 UBQLN2 UBQLN4 USP20 VEZF1
Entrez ID		83758	10551
HPRD ID		17961	05896
Ensembl ID		ENSG00000139194	ENSG00000106541
Uniprot IDs		P82980	O95994 Q4JM46
PDB IDs		1GGL 6E5W 9BCB	2LNS 2LNT
Enriched GO Terms of Interacting Partners?		Carbohydrate Derivative Transmembrane Transporter Activity CGMP Transport Macromolecule Transmembrane Transporter Activity Spermatogonial Cell Division Hyaluronan Biosynthetic Process Heme Transmembrane Transport Folate Transmembrane Transport Purine Nucleotide Transmembrane Transporter Activity CAMP Transport Lung Goblet Cell Differentiation Positive Regulation Of PERK-mediated Unfolded Protein Response DNA Replication-dependent Chromatin Assembly Peroxisome Proliferator Activated Receptor Binding Folic Acid Transport Cyclic Nucleotide Transport Glutathione Transmembrane Transporter Activity Heme Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity Glutathione Transport Glutathione Transmembrane Transport Heme Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Dystroglycan Binding Positive Regulation Of IRE1-mediated Unfolded Protein Response Nuclear Retinoid X Receptor Binding Nuclear Retinoic Acid Receptor Binding Oligopeptide Transport Xenobiotic Export From Cell ABC-type Xenobiotic Transporter Activity Iron Ion Transmembrane Transport Oligopeptide Transmembrane Transport Glycosaminoglycan Biosynthetic Process Xenobiotic Transmembrane Transport Vitamin Transmembrane Transport Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Mucus Secretion Organic Anion Transmembrane Transporter Activity Positive Regulation Of Protein Localization Digestive Tract Morphogenesis Xenobiotic Transmembrane Transporter Activity Hyaluronan Metabolic Process Lung Epithelial Cell Differentiation Lung Cell Differentiation Nuclear Thyroid Hormone Receptor Binding ATPase-coupled Transmembrane Transporter Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Adenine Nucleotide Transport	Nuclear Pore Structural Constituent Of Nuclear Pore TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress GET Complex Tail-anchored Membrane Protein Insertion Into ER Membrane RNA Transport Positive Regulation Of ERAD Pathway Protein Binding Nucleus Homologous Chromosome Segregation Regulation Of ERAD Pathway
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