RBP5 and NR0B2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RBP5	NR0B2
Description		retinol binding protein 5	nuclear receptor subfamily 0 group B member 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Exosome	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex
	Molecular Function	Retinoid Binding Fatty Acid Binding Protein Binding Lipid Binding Retinal Binding Retinol Binding	Transcription Corepressor Activity Protein Binding Nuclear Receptor Binding Protein Domain Specific Binding Protein Homodimerization Activity Nuclear Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Protein-containing Complex Binding Nuclear Retinoid X Receptor Binding Nuclear Thyroid Hormone Receptor Binding Transcription Regulator Inhibitor Activity
	Biological Process	Fatty Acid Transport	Negative Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Circadian Rhythm Cholesterol Metabolic Process Response To Glucose Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Animal Organ Regeneration Positive Regulation Of Insulin Secretion Circadian Regulation Of Gene Expression Negative Regulation Of DNA-binding Transcription Factor Activity Response To Ethanol Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Rhythmic Process
Pathways			Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494) Refractive error ( 32231278)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068) LDL cholesterol ( 24097068) Triglycerides ( 24097068)
Interacting Genes		5 interacting genes: ABCC5 AGR2 CCNDBP1 H3-4 NR0B2	51 interacting genes: AR CHRD CIDEC DDX20 EID1 ESR1 ESR2 ESRRA ESRRG FN1 GPS2 GPSM3 HDAC3 HDAC6 HNF4A HNF4G HNRNPA1 ID2 IL3RA NCOA3 NEUROD1 NR1H2 NR1H3 NR1I2 NR1I3 NR3C1 NR5A2 PAX9 PEF1 PLSCR1 POLR2A PPARD PPARG RARA RARG RBP5 RNF31 RXRA RXRB RXRG SMAD4 SMARCA2 SMARCB1 SMARCE1 SNW1 THRA TP53 VDR XBP1 ZAP70 ZMYND10
Entrez ID		83758	8431
HPRD ID		17961	05219
Ensembl ID		ENSG00000139194	ENSG00000131910
Uniprot IDs		P82980	Q15466
PDB IDs		1GGL 6E5W 9BCB	1YUC 2Q3Y 2Z4J 4DOR 4ONI 5UFS 6W9M 7YXC 7YXD 7YXN 7YXO 7YXP 7YXR
Enriched GO Terms of Interacting Partners?		Carbohydrate Derivative Transmembrane Transporter Activity CGMP Transport Macromolecule Transmembrane Transporter Activity Spermatogonial Cell Division Hyaluronan Biosynthetic Process Heme Transmembrane Transport Folate Transmembrane Transport Purine Nucleotide Transmembrane Transporter Activity CAMP Transport Lung Goblet Cell Differentiation Positive Regulation Of PERK-mediated Unfolded Protein Response DNA Replication-dependent Chromatin Assembly Peroxisome Proliferator Activated Receptor Binding Folic Acid Transport Cyclic Nucleotide Transport Glutathione Transmembrane Transporter Activity Heme Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity Glutathione Transport Glutathione Transmembrane Transport Heme Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Dystroglycan Binding Positive Regulation Of IRE1-mediated Unfolded Protein Response Nuclear Retinoid X Receptor Binding Nuclear Retinoic Acid Receptor Binding Oligopeptide Transport Xenobiotic Export From Cell ABC-type Xenobiotic Transporter Activity Iron Ion Transmembrane Transport Oligopeptide Transmembrane Transport Glycosaminoglycan Biosynthetic Process Xenobiotic Transmembrane Transport Vitamin Transmembrane Transport Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Mucus Secretion Organic Anion Transmembrane Transporter Activity Positive Regulation Of Protein Localization Digestive Tract Morphogenesis Xenobiotic Transmembrane Transporter Activity Hyaluronan Metabolic Process Lung Epithelial Cell Differentiation Lung Cell Differentiation Nuclear Thyroid Hormone Receptor Binding ATPase-coupled Transmembrane Transporter Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Adenine Nucleotide Transport	Nuclear Receptor Activity Intracellular Receptor Signaling Pathway Hormone-mediated Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Retinoic Acid Receptor Signaling Pathway Chromatin Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA Binding Nuclear Steroid Receptor Activity RNA Polymerase II Transcription Regulator Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Regulation Of Gene Expression RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Nucleoplasm DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Intracellular Signal Transduction Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Cellular Developmental Process Cell Differentiation MRNA Transcription DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process
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