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L3MBTL2 and PAICS
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
L3MBTL2
PAICS
Gene Name
l(3)mbt-like 2 (Drosophila)
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Zinc Ion Binding
Methylated Histone Binding
Histone Binding
Phosphoribosylaminoimidazole Carboxylase Activity
Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity
Protein Binding
ATP Binding
Identical Protein Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Chromatin Modification
Purine Nucleobase Metabolic Process
'de Novo' IMP Biosynthetic Process
Purine Nucleobase Biosynthetic Process
Purine Ribonucleoside Monophosphate Biosynthetic Process
Small Molecule Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Pathways
Purine ribonucleoside monophosphate biosynthesis
Purine metabolism
Metabolism of nucleotides
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
AES
CBX3
HIST1H3A
HIST1H4A
MEAF6
MPP3
PAICS
PHF10
PIAS1
RNF2
STAC3
STAM2
TBC1D9B
TRIM42
11 interactors:
CEP76
CHD3
FXR2
L3MBTL2
LNX1
MOB4
NIF3L1
NUDT18
PRKAG1
SMARCD1
TERF1
Entrez ID
83746
10606
HPRD ID
13954
01401
Ensembl ID
ENSG00000100395
ENSG00000128050
Uniprot IDs
Q969R5
P22234
PDB IDs
2W0T
3CEY
3F70
2H31
Enriched GO Terms of Interacting Partners
?
DNA Replication-dependent Nucleosome Assembly
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
DNA Methylation On Cytosine
Chromatin Organization
Cellular Nitrogen Compound Metabolic Process
Chromatin Silencing At RDNA
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Nitrogen Compound Metabolic Process
Protein-DNA Complex Assembly
Gene Expression
Chromosome Organization
Chromatin Silencing
Chromatin Modification
Negative Regulation Of Cellular Metabolic Process
DNA Methylation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
DNA Modification
Histone Modification
Histone H2A-K119 Monoubiquitination
Gene Silencing
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Histone H4-K20 Demethylation
Regulation Of Cellular Process
Nucleosome Assembly
Positive Regulation Of Anoikis
Chromatin Assembly
Negative Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Smooth Muscle Cell Differentiation
Nucleosome Organization
Chromatin Assembly Or Disassembly
'de Novo' IMP Biosynthetic Process
Histone H3-K14 Acetylation
RNA Metabolic Process
Cellular Macromolecular Complex Assembly
Chromatin Remodeling
DNA Packaging
Negative Regulation Of Hematopoietic Progenitor Cell Differentiation
Chromatin Modification
Chromatin Organization
GDP Catabolic Process
DGDP Catabolic Process
DADP Catabolic Process
Chromosome Organization
Protein Oligomerization
Cell Cycle Process
7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Organelle Organization
G2/M Transition Of Mitotic Cell Cycle
Telomeric Loop Formation
Age-dependent Telomere Shortening
Dihydrobiopterin Metabolic Process
Telomere Maintenance Via Telomere Shortening
Regulation Of Microtubule Cytoskeleton Organization
Chromatin Assembly Or Disassembly
Cell Cycle
Purine Ribonucleoside Diphosphate Catabolic Process
Nucleobase-containing Small Molecule Catabolic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Microtubule-based Process
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Diphosphate Catabolic Process
Replicative Cell Aging
Regulation Of Nuclear Cell Cycle DNA Replication
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Chromatin-mediated Maintenance Of Transcription
Deoxyribonucleoside Diphosphate Metabolic Process
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Centriole Replication
Purine Ribonucleoside Catabolic Process
Protein Homooligomerization
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Positive Regulation Of Microtubule Polymerization
Nucleosome Disassembly
Regulation Of Telomerase Activity
Regulation Of Cell Cycle
Deoxyribose Phosphate Catabolic Process
Positive Regulation Of Gene Expression, Epigenetic
Regulation Of Telomere Maintenance
Protein Complex Assembly
RNA-dependent DNA Replication
Negative Regulation Of DNA Biosynthetic Process
Purine Ribonucleotide Catabolic Process
Regulation Of Glycolytic Process
Tagcloud
?
700r
analyse
balancing
compaction
competent
defective
dub
essentially
facilitates
flag
h2aub1
hek293
integral
k675
lethal
occupancy
occupied
polycomb
prc1
repressed
repressive
ring2
seq
stably
sumo2
sumoylation
tagged
tails
ubiquitinating
Tagcloud (Difference)
?
700r
analyse
balancing
compaction
competent
defective
dub
essentially
facilitates
flag
h2aub1
hek293
integral
k675
lethal
occupancy
occupied
polycomb
prc1
repressed
repressive
ring2
seq
stably
sumo2
sumoylation
tagged
tails
ubiquitinating
Tagcloud (Intersection)
?