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JAM3 and ITGAX
Number of citations of the paper that reports this interaction (PMID
12208882
)
65
Data Source:
HPRD
(in vivo)
JAM3
ITGAX
Gene Name
junctional adhesion molecule 3
integrin, alpha X (complement component 3 receptor 4 subunit)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Golgi Apparatus
Plasma Membrane
Tight Junction
Integral Component Of Membrane
Desmosome
Paranodal Junction
Schmidt-Lanterman Incisure
Cell-cell Contact Zone
Plasma Membrane
Integrin Complex
Cell Surface
Membrane
Molecular Function
Integrin Binding
Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Receptor Activity
Protein Binding
Metal Ion Binding
Biological Process
Angiogenesis
Neutrophil Homeostasis
Adaptive Immune Response
Myeloid Progenitor Cell Differentiation
Leukocyte Migration Involved In Inflammatory Response
Cell-matrix Adhesion
Spermatid Development
Blood Coagulation
Transmission Of Nerve Impulse
Establishment Of Cell Polarity
Extracellular Matrix Organization
Axon Regeneration
Myelination
Leukocyte Migration
Regulation Of Neutrophil Chemotaxis
Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion
Cell Adhesion
Integrin-mediated Signaling Pathway
Blood Coagulation
Organ Morphogenesis
Extracellular Matrix Organization
Heterotypic Cell-cell Adhesion
Leukocyte Migration
Pathways
Integrin cell surface interactions
Cell surface interactions at the vascular wall
ECM proteoglycans
Integrin cell surface interactions
Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Systemic lupus erythematosus (
18204098
)
Protein-Protein Interactions
6 interactors:
F2RL2
ITGAM
ITGAX
JAM2
PICK1
TJP1
4 interactors:
C3
FCER2
ITGB2
JAM3
Entrez ID
83700
3687
HPRD ID
06042
01051
Ensembl ID
ENSG00000166086
ENSG00000140678
Uniprot IDs
Q9BX67
H3BN02
P20702
Q8TES5
PDB IDs
1N3Y
2LUV
3K6S
3K71
3K72
Enriched GO Terms of Interacting Partners
?
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Response To Wounding
Leukocyte Migration
Extracellular Matrix Organization
Extracellular Structure Organization
Single Organismal Cell-cell Adhesion
Cell-cell Signaling Involved In Cell-cell Junction Organization
Glial Cell Development
Response To Stress
Integrin-mediated Signaling Pathway
Response To External Stimulus
Microglia Development
Cell Migration
Glial Cell Differentiation
Response To Magnetism
Cell Motility
Ectodermal Cell Differentiation
Gliogenesis
Establishment Of Endothelial Intestinal Barrier
Response To Stimulus
DNA Methylation Involved In Embryo Development
Cell Adhesion
Dendritic Spine Maintenance
Signal Transduction
Locomotion
Neuronal Ion Channel Clustering
Thrombin Receptor Signaling Pathway
Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Negative Regulation Of Vascular Permeability
Negative Regulation Of Actin Nucleation
Cell Surface Receptor Signaling Pathway
Signaling
Cell Communication
Movement Of Cell Or Subcellular Component
Long Term Synaptic Depression
Leukocyte Migration Involved In Inflammatory Response
Positive Regulation Of Receptor Internalization
Macrophage Differentiation
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Dendritic Spine Organization
Heterotypic Cell-cell Adhesion
DNA Methylation Involved In Gamete Generation
Regulation Of Actin Nucleation
Ectoderm Development
Cellular Response To Glucose Starvation
Monoamine Transport
Cellular Component Maintenance
Leukocyte Migration Involved In Inflammatory Response
Positive Regulation Of Humoral Immune Response
Regulation Of Immune System Process
Positive Regulation Of Immunoglobulin Mediated Immune Response
Inflammatory Response
Regulation Of Humoral Immune Response
Positive Regulation Of Immune Response
Positive Regulation Of Angiogenesis
Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Positive Regulation Of Adaptive Immune Response
Cell-matrix Adhesion
Positive Regulation Of Type IIa Hypersensitivity
Regulation Of Adaptive Immune Response
Cell-substrate Adhesion
Regulation Of Angiogenesis
Leukocyte Migration
Positive Regulation Of Activation Of Membrane Attack Complex
Immune Response
Defense Response
Adaptive Immune Response
Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Positive Regulation Of Hypersensitivity
Positive Regulation Of Apoptotic Cell Clearance
Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Extracellular Matrix Organization
Extracellular Structure Organization
Myeloid Progenitor Cell Differentiation
Positive Regulation Of Killing Of Cells Of Other Organism
Regulation Of Killing Of Cells Of Other Organism
Regulation Of Apoptotic Cell Clearance
Blood Coagulation
Hemostasis
Complement Activation, Alternative Pathway
Positive Regulation Of Inflammatory Response To Antigenic Stimulus
Regulation Of Cellular Component Organization
Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process
Neutrophil Homeostasis
Single Organismal Cell-cell Adhesion
Immune System Process
Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Positive Regulation Of Nitric-oxide Synthase Activity
Positive Regulation Of Protein Processing
Regulation Of Triglyceride Biosynthetic Process
Signaling
Regulation Of Body Fluid Levels
Cell Communication
Wound Healing
Heterotypic Cell-cell Adhesion
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