JAM3 and TJP1

Number of citations of the paper that reports this interaction (PMID 12953056)
42

Data Source:
HPRD (in vitro, in vivo)

		JAM3	TJP1
Gene Name		junctional adhesion molecule 3	tight junction protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Golgi Apparatus Plasma Membrane Tight Junction Integral Component Of Membrane Desmosome Paranodal Junction Schmidt-Lanterman Incisure Cell-cell Contact Zone	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Adherens Junction Gap Junction Tight Junction Intercalated Disc Basolateral Plasma Membrane Apical Plasma Membrane Apicolateral Plasma Membrane Cell Junction Apical Junction Complex Apical Part Of Cell Intercellular Canaliculus
	Molecular Function	Integrin Binding Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Protein Binding Calmodulin Binding Protein C-terminus Binding Protein Domain Specific Binding
	Biological Process	Angiogenesis Neutrophil Homeostasis Adaptive Immune Response Myeloid Progenitor Cell Differentiation Leukocyte Migration Involved In Inflammatory Response Cell-matrix Adhesion Spermatid Development Blood Coagulation Transmission Of Nerve Impulse Establishment Of Cell Polarity Extracellular Matrix Organization Axon Regeneration Myelination Leukocyte Migration Regulation Of Neutrophil Chemotaxis Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion	Blastocyst Formation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell-cell Junction Assembly Sensory Perception Of Sound Response To Lipopolysaccharide Hippo Signaling Response To Drug Negative Regulation Of Vascular Permeability Response To Ethanol Membrane Organization Response To Magnetism Cellular Response To Glucose Stimulus Establishment Of Endothelial Intestinal Barrier Cell-cell Signaling Involved In Cell-cell Junction Organization
Pathways		Integrin cell surface interactions Cell surface interactions at the vascular wall	Apoptotic cleavage of cell adhesion proteins c-src mediated regulation of Cx43 function and closure of gap junctions Apoptotic cleavage of cellular proteins Signaling by Hippo Gap junction trafficking and regulation Programmed Cell Death Apoptotic execution phase Regulation of gap junction activity
Drugs
Diseases
GWAS			Corneal structure ( 23291589) Response to antipsychotic treatment ( 23241943)
Protein-Protein Interactions		6 interactors: F2RL2 ITGAM ITGAX JAM2 PICK1 TJP1	38 interactors: ACTA1 ACTN4 ARVCF CGN CLDN1 CLDN16 CLDN2 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CNKSR2 CTNNA1 CTTN EGFR F11R GJA1 GJA3 GJA8 GJB3 GJC1 GJD3 GRIN1 GRIN2D HSP90AA1 JAM2 JAM3 KHDRBS1 KIRREL MLLT4 PTPN14 TJP2 TJP3 TRPC4 UBN1 YBX3
Entrez ID		83700	7082
HPRD ID		06042	03002
Ensembl ID		ENSG00000166086	ENSG00000104067
Uniprot IDs		Q9BX67	G3V1L9 Q07157 Q6MZU1
PDB IDs			2H2B 2H2C 2H3M 2JWE 2KXR 2KXS 2RCZ 3CYY 3LH5 3SHU 3SHW 3TSV 3TSW 3TSZ
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Leukocyte Migration Extracellular Matrix Organization Extracellular Structure Organization Single Organismal Cell-cell Adhesion Cell-cell Signaling Involved In Cell-cell Junction Organization Glial Cell Development Response To Stress Integrin-mediated Signaling Pathway Response To External Stimulus Microglia Development Cell Migration Glial Cell Differentiation Response To Magnetism Cell Motility Ectodermal Cell Differentiation Gliogenesis Establishment Of Endothelial Intestinal Barrier Response To Stimulus DNA Methylation Involved In Embryo Development Cell Adhesion Dendritic Spine Maintenance Signal Transduction Locomotion Neuronal Ion Channel Clustering Thrombin Receptor Signaling Pathway Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Vascular Permeability Negative Regulation Of Actin Nucleation Cell Surface Receptor Signaling Pathway Signaling Cell Communication Movement Of Cell Or Subcellular Component Long Term Synaptic Depression Leukocyte Migration Involved In Inflammatory Response Positive Regulation Of Receptor Internalization Macrophage Differentiation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Dendritic Spine Organization Heterotypic Cell-cell Adhesion DNA Methylation Involved In Gamete Generation Regulation Of Actin Nucleation Ectoderm Development Cellular Response To Glucose Starvation Monoamine Transport Cellular Component Maintenance	Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Junction Assembly Cell-cell Junction Assembly Gap Junction Assembly Cell Development Establishment Of Endothelial Intestinal Barrier Anatomical Structure Development Cellular Component Assembly Developmental Process Epithelial Cell Development Apical Junction Assembly Establishment Of Endothelial Barrier Endothelium Development Neuron Projection Development Regulation Of Body Fluid Levels Response To Abiotic Stimulus Regulation Of Actin Filament-based Process Anatomical Structure Morphogenesis Tight Junction Assembly Transmembrane Transport Endothelial Cell Development Response To Organic Substance System Development Movement Of Cell Or Subcellular Component Neuron Development Cell Differentiation Atrial Cardiac Muscle Cell Action Potential Atrial Cardiac Muscle Cell To AV Node Cell Communication Multicellular Organismal Development Locomotion Cell Communication Single Organismal Cell-cell Adhesion Epithelial Cell Differentiation Cell Morphogenesis Axon Development Endothelial Cell Differentiation Neuron Differentiation Cell-cell Signaling Involved In Cardiac Conduction Cell Projection Organization Positive Regulation Of Rap GTPase Activity Neurological System Process Establishment Of Skin Barrier Adherens Junction Organization Skin Development Neuron Projection Morphogenesis Cell-cell Signaling
Tagcloud ?			abp androgen ar blots clonal clu constitutes fshr hampering immortalized immunocytochemistry inhbb investigations loose mediators microarrays posttranslational responsiveness rhox5 sc sertoli sox9 spermatogenesis spinlw1 st38c stabilization testosterone undergoes wt1
Tagcloud (Difference) ?			abp androgen ar blots clonal clu constitutes fshr hampering immortalized immunocytochemistry inhbb investigations loose mediators microarrays posttranslational responsiveness rhox5 sc sertoli sox9 spermatogenesis spinlw1 st38c stabilization testosterone undergoes wt1
Tagcloud (Intersection) ?