DYNLRB1 and PALS2

Number of citations of the paper that reports this interaction (PubMedID 15231747)
47

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DYNLRB1	PALS2
Description		dynein light chain roadblock-type 1	protein associated with LIN7 2, MAGUK p55 family member
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Cytoplasmic Dynein Complex Microtubule Cilium Membrane Dynein Complex Ciliary Tip	Plasma Membrane Cell-cell Junction Membrane Organelle Extracellular Exosome
	Molecular Function	Microtubule Motor Activity Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding	Protein Binding
	Biological Process	Microtubule-based Movement Visual Behavior Positive Regulation Of Intracellular Transport	Protein-containing Complex Assembly
Pathways		Intraflagellar transport
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Pulse pressure ( 30224653)
Interacting Genes		10 interacting genes: CEBPA CPEB1 CRCP DYNC1I1 DYNC1I2 HSPH1 MAGEA2 MAGEA2B MPHOSPH6 PALS2	31 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A MT2P1 MTREX NDN NFKB1 OGT PARN RPS20 SMARCA4 SNX9 THOP1 VPS26C WEE2-AS1
Entrez ID		83658	51678
HPRD ID		06203	09509
Ensembl ID		ENSG00000125971	ENSG00000105926
Uniprot IDs		B4DFR2 Q9NP97	B8ZZG1 Q9NZW5
PDB IDs		1Z09 2B95 2E8J 2HZ5 6F1T 6F1Z 6F38 6F3A 6RLB 6SC2 7Z8F 8J07 8PR1 8PTK 8RGG 8RGH
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Acetylation Dynein Light Chain Binding Negative Regulation Of Protein Sumoylation Dynein Heavy Chain Binding Positive Regulation Of Ubiquitin-protein Transferase Activity Histone Deacetylase Binding Cytoplasmic Dynein Complex Regulation Of Protein Sumoylation Regulation Of Ubiquitin-protein Transferase Activity DNA-binding Transcription Factor Binding Dynein Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Microtubule Motor Activity Cellular Senescence DNA Polymerase III Complex Microtubule Response To Vitamin B2 C/EBP Complex RNA Polymerase Complex Negative Regulation Of Post-translational Protein Modification Signal Transduction By P53 Class Mediator CHOP-C/EBP Complex Positive Regulation Of Protein Ubiquitination PML Body White Fat Cell Proliferation Calcitonin Gene-related Peptide Receptor Activity Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of MHC Class I Biosynthetic Process Response To Phenylpropanoid Negative Regulation Of Protein Metabolic Process Regulation Of MHC Class I Biosynthetic Process Transcription Initiation At RNA Polymerase III Promoter	Nuclear Exosome (RNase Complex) Exosome (RNase Complex) Cytoplasmic Exosome (RNase Complex) Nucleolar Exosome (RNase Complex) Nuclear MRNA Surveillance RNA Exonuclease Activity U4 SnRNA 3'-end Processing Nuclear RNA Surveillance RNA Surveillance 3'-5'-RNA Exonuclease Activity RRNA Catabolic Process SnRNA Metabolic Process Poly(A)-dependent SnoRNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process SnRNA 3'-end Processing RNA 3'-end Processing MRNA Catabolic Process RNA Catabolic Process Exoribonuclease Complex SnRNA Processing Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRNA Surveillance TRAMP-dependent TRNA Surveillance Pathway Nuclear Polyadenylation-dependent RRNA Catabolic Process Sno(s)RNA Metabolic Process RRNA 3'-end Processing TRNA Decay RRNA Processing RRNA Metabolic Process Nucleobase-containing Compound Catabolic Process MRNA Metabolic Process RNA Binding U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Nucleolus RNA Metabolic Process CUT Catabolic Process RNA Processing Negative Regulation Of Gene Expression MRNA 3'-UTR AU-rich Region Binding Macromolecule Catabolic Process DNA Deamination Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleic Acid Metabolic Process Maturation Of 5.8S RRNA Cytoplasm Catabolic Process DNA Modification Negative Regulation Of Macromolecule Metabolic Process
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