DYNLRB1 and CRCP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DYNLRB1	CRCP
Description		dynein light chain roadblock-type 1	CGRP receptor component
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton Cytoplasmic Dynein Complex Microtubule Cilium Membrane Dynein Complex Ciliary Tip	DNA-directed RNA Polymerase Complex Acrosomal Vesicle Nucleus Nucleoplasm RNA Polymerase III Complex Cytosol Plasma Membrane DNA Polymerase III Complex Membrane RNA Polymerase Complex
	Molecular Function	Microtubule Motor Activity Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding	Nucleotide Binding Calcitonin Gene-related Peptide Receptor Activity DNA-directed RNA Polymerase Activity Protein Binding
	Biological Process	Microtubule-based Movement Visual Behavior Positive Regulation Of Intracellular Transport	Immune System Process DNA-templated Transcription Initiation Transcription By RNA Polymerase III Transcription Initiation At RNA Polymerase III Promoter Neuropeptide Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways		Intraflagellar transport	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Bipolar disorder ( 31043756) Colorectal cancer or advanced adenoma ( 30510241) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Pulse pressure ( 30224653)	Aortic root size ( 21223598) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		10 interacting genes: CEBPA CPEB1 CRCP DYNC1I1 DYNC1I2 HSPH1 MAGEA2 MAGEA2B MPHOSPH6 PALS2	9 interacting genes: AGR2 CALCRL DYNLRB1 GSC2 LRIF1 POLR3H TCF12 VAV2 ZMIZ2
Entrez ID		83658	27297
HPRD ID		06203	12089
Ensembl ID		ENSG00000125971	ENSG00000241258
Uniprot IDs		B4DFR2 Q9NP97	O75575
PDB IDs		1Z09 2B95 2E8J 2HZ5 6F1T 6F1Z 6F38 6F3A 6RLB 6SC2 7Z8F 8J07 8PR1 8PTK 8RGG 8RGH	7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59 7DN3 7DU2 7FJI 7FJJ 8ITY 8IUE 8IUH 9FSO 9FSP 9FSQ 9FSR 9FSS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Acetylation Dynein Light Chain Binding Negative Regulation Of Protein Sumoylation Dynein Heavy Chain Binding Positive Regulation Of Ubiquitin-protein Transferase Activity Histone Deacetylase Binding Cytoplasmic Dynein Complex Regulation Of Protein Sumoylation Regulation Of Ubiquitin-protein Transferase Activity DNA-binding Transcription Factor Binding Dynein Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Microtubule Motor Activity Cellular Senescence DNA Polymerase III Complex Microtubule Response To Vitamin B2 C/EBP Complex RNA Polymerase Complex Negative Regulation Of Post-translational Protein Modification Signal Transduction By P53 Class Mediator CHOP-C/EBP Complex Positive Regulation Of Protein Ubiquitination PML Body White Fat Cell Proliferation Calcitonin Gene-related Peptide Receptor Activity Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of MHC Class I Biosynthetic Process Response To Phenylpropanoid Negative Regulation Of Protein Metabolic Process Regulation Of MHC Class I Biosynthetic Process Transcription Initiation At RNA Polymerase III Promoter	Epidermal Growth Factor Receptor Binding
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