MPP6 and DYNLRB1

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MPP6	DYNLRB1
Gene Name		membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)	dynein, light chain, roadblock-type 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Extracellular Vesicular Exosome	Cytoplasm Centrosome Cytoplasmic Dynein Complex Microtubule Membrane Primary Cilium Ciliary Tip
	Molecular Function	Protein Binding PDZ Domain Binding	Microtubule Motor Activity
	Biological Process	Protein Complex Assembly	Transport Organelle Organization Microtubule-based Movement Visual Behavior Metabolic Process
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A MT2P1 NDN NFKB1 PARN RPS20 SKIV2L2 SMARCA4 SNX9 THOP1	6 interactors: CPEB1 DYNC1I1 DYNC1I2 HSPH1 MPHOSPH6 MPP6
Entrez ID		51678	83658
HPRD ID		09509	06203
Ensembl ID		ENSG00000105926	ENSG00000125971
Uniprot IDs		B8ZZG1 Q9NZW5	B4DFR2 Q9NP97
PDB IDs			1Z09 2B95 2E8J 2HZ5
Enriched GO Terms of Interacting Partners?		Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic MRNA Catabolic Process RNA Catabolic Process Ribosome Biogenesis RRNA Processing RRNA Metabolic Process Ribonucleoprotein Complex Biogenesis MRNA Metabolic Process RNA Phosphodiester Bond Hydrolysis Aromatic Compound Catabolic Process Nuclear MRNA Surveillance NcRNA Metabolic Process RNA Surveillance RRNA Catabolic Process Cellular Macromolecule Catabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis Maturation Of 5.8S RRNA Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Gene Expression RNA Metabolic Process DNA Deamination Catabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process DNA Modification Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Growth Histone MRNA Catabolic Process Regulation Of Growth Intracellular MRNA Localization Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Protein-lipid Complex Assembly Histone MRNA Metabolic Process Membrane Organization Positive Regulation Of Cell Growth Cellular Process RNA Processing Cellular Metabolic Process Regulation Of Cholesterol Transport Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Interleukin-12 Biosynthetic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Neurotrophin TRK Receptor Signaling Pathway See more	Maturation Of 5.8S RRNA Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II RRNA Processing RRNA Metabolic Process Ribosome Biogenesis Positive Regulation Of NK T Cell Activation Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of Cytoplasmic Translation Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Microtubule-based Movement Regulation Of Cytoplasmic Translation Ribonucleoprotein Complex Biogenesis Regulation Of MHC Class I Biosynthetic Process Synaptonemal Complex Assembly NcRNA Metabolic Process Synaptonemal Complex Organization Chaperone Mediated Protein Folding Requiring Cofactor See more
Tagcloud ?		binds cofactor cofactors composite conserved core create crystallographic disrupts exo exoribonuclease exosome functionally gfp groove helicase insight interface intertwined mtr4 physically revealing ribonuclease rnas rrp47 rrp6 structural synergize turnover	associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll2 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Difference) ?		binds cofactor cofactors composite conserved core create crystallographic disrupts exo exoribonuclease exosome functionally gfp groove helicase insight interface intertwined mtr4 physically revealing ribonuclease rnas rrp47 rrp6 structural synergize turnover	associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll2 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Intersection) ?