COG3 and DCTN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COG3	DCTN2
Description		component of oligomeric golgi complex 3	dynactin subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cis-Golgi Network Cytosol Plasma Membrane Membrane Golgi Transport Complex Golgi Cisterna Membrane Trans-Golgi Network Membrane	Kinetochore Cytoplasm Centrosome Cytosol Cytoskeleton Dynactin Complex Microtubule Membrane Dynein Complex Growth Cone Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Spectrin Binding Identical Protein Binding
	Biological Process	Retrograde Transport, Vesicle Recycling Within Golgi Protein Glycosylation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Protein Localization To Organelle Protein Stabilization Glycosylation	Microtubule-based Process Mitotic Spindle Organization Mitotic Metaphase Chromosome Alignment Melanosome Transport Protein Localization To Centrosome
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2
Drugs
Diseases
GWAS		Breast milk fatty acid composition (infant genotype effect) ( 29514873) Breast milk fatty acid composition (maternal genotype effect) ( 29514873)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		11 interacting genes: ABI2 CINP COG1 COG2 DCTN2 KIFC3 NUP58 SPG21 TRIM2 TSHZ2 ZDHHC17	39 interacting genes: ABI2 BICD1 BICD2 BLOC1S1 BLOC1S2 BLOC1S6 CALM1 CCDC172 CENPH CEP44 COG3 DISC1 EGFR FXR1 FXR2 GADD45A GADD45G GNAO1 GOLM1 GRB2 GSK3B HAUS1 HGS KIFC3 KPNA2 MAPK6 MAPRE3 MARCKSL1 OGT PAFAH1B1 RABGEF1 RINT1 RPGR SHANK3 SMARCD1 TSC1 TXLNB USHBP1 ZW10
Entrez ID		83548	10540
HPRD ID		08443	09568
Ensembl ID		ENSG00000136152	ENSG00000175203
Uniprot IDs		Q96JB2	A0A384MDU9 A8K8J9 B3KTX4 Q13561 V9HW58
PDB IDs
Enriched GO Terms of Interacting Partners?		Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Golgi Organization Intra-Golgi Vesicle-mediated Transport Adherens Junction Organization Perforant Pathway To Dendrate Granule Cell Synapse Golgi Apparatus Zonula Adherens Assembly Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission	Microtubule-based Process Organelle Organization Organelle Assembly Transport Along Microtubule Centrosome Cytoskeleton-dependent Intracellular Transport Cytoplasm Microtubule-based Transport Dynactin Binding Organelle Transport Along Microtubule Organelle Localization Cellular Localization Establishment Of Organelle Localization Regulation Of Dendritic Spine Development Membraneless Organelle Assembly Microtubule-based Movement Regulation Of Cytoskeleton Organization Microtubule Cytoskeleton Organization Intracellular Signal Transduction Positive Regulation Of Long-term Neuronal Synaptic Plasticity Protein Localization To Organelle Intracellular Transport Axo-dendritic Transport Cytosol Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Dendritic Spine Development Cytoskeleton Regulation Of Dendritic Spine Morphogenesis Vesicle Transport Along Microtubule Intracellular Protein Localization Establishment Of Localization In Cell Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum BLOC-1 Complex Regulation Of Multicellular Organismal Process Anterograde Synaptic Vesicle Transport Regulation Of Organelle Organization Vesicle Cytoskeletal Trafficking Cytoskeleton Organization Positive Regulation Of Neurogenesis Axon Cytoplasm Modulation Of Chemical Synaptic Transmission Dynein Complex Binding Axonal Transport Central Region Of Growth Cone Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Dsl1/NZR Complex Intracellular Signaling Cassette Cytoskeletal Anchor Activity Regulation Of Postsynapse Organization Regulation Of Microtubule-based Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?