COG3 and NUP58

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COG3	NUP58
Description		component of oligomeric golgi complex 3	nucleoporin 58
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cis-Golgi Network Cytosol Plasma Membrane Membrane Golgi Transport Complex Golgi Cisterna Membrane Trans-Golgi Network Membrane	Nucleus Nuclear Envelope Nuclear Pore Membrane Nuclear Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Retrograde Transport, Vesicle Recycling Within Golgi Protein Glycosylation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Protein Localization To Organelle Protein Stabilization Glycosylation	Nucleocytoplasmic Transport Protein Transport Regulation Of Protein Import Into Nucleus MRNA Transport
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Breast milk fatty acid composition (infant genotype effect) ( 29514873) Breast milk fatty acid composition (maternal genotype effect) ( 29514873)
Interacting Genes		11 interacting genes: ABI2 CINP COG1 COG2 DCTN2 KIFC3 NUP58 SPG21 TRIM2 TSHZ2 ZDHHC17	19 interacting genes: ABI3 AGR2 APC COG3 COG6 HTT KRT27 KRT28 KRT33B MAPK3 MEIS2 MIS18A NUP62 PKNOX1 PKNOX2 TRAF1 TRIM54 UBQLN1 UBQLN2
Entrez ID		83548	9818
HPRD ID		08443	06355
Ensembl ID		ENSG00000136152	ENSG00000139496
Uniprot IDs		Q96JB2	A0A8Q3WKK5 A0A8Q3WKL7 Q9BVL2
PDB IDs			4JO7 4JO9 4JQ5 5IJN 5IJO 7PER 7R5J 7R5K
Enriched GO Terms of Interacting Partners?		Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Golgi Organization Intra-Golgi Vesicle-mediated Transport Adherens Junction Organization Perforant Pathway To Dendrate Granule Cell Synapse Golgi Apparatus Zonula Adherens Assembly Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission	Positive Regulation Of Protein Localization To Centrosome Regulation Of Protein Localization To Centrosome Organelle Organization Regulation Of Macroautophagy Structural Constituent Of Skin Epidermis Intermediate Filament Organization Positive Regulation Of Response To Endoplasmic Reticulum Stress Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Anatomical Structure Morphogenesis Autophagosome Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Autophagosome Assembly Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of ERAD Pathway Regulation Of Organelle Assembly Autophagosome Organization Regulation Of Organelle Organization Golgi Organization Regulation Of ERAD Pathway Positive Regulation Of Catabolic Process Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Hair Follicle Morphogenesis Identical Protein Binding Positive Regulation Of ERBB Signaling Pathway Intra-Golgi Vesicle-mediated Transport Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule Depolymerization Regulation Of Protein Catabolic Process Regulation Of Protein Stability Regulation Of Autophagy Intermediate Filament Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Microtubule Polymerization Or Depolymerization Cytoskeleton Epithelial Cell Differentiation Structural Molecule Activity Vacuole Organization Negative Regulation Of Store-operated Calcium Channel Activity Tissue Morphogenesis Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Peptidyl-tyrosine Phosphorylation Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of G Protein-coupled Receptor Internalization
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