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HIST1H2AJ and PTMA
Number of citations of the paper that reports this interaction (PMID
8814229
)
9
Data Source:
HPRD
(in vitro)
HIST1H2AJ
PTMA
Gene Name
histone cluster 1, H2aj
prothymosin, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Biological Process
Transcription, DNA-templated
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
Deposition of new CENPA-containing nucleosomes at the centromere
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
Packaging Of Telomere Ends
Telomere Maintenance
Nucleosome assembly
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Meiotic synapsis
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Eating disorders (purging via substances) (
23568457
)
Height (
18391951
)
Protein-Protein Interactions
1 interactors:
PTMA
41 interactors:
CASP3
CASP7
CCNA2
CCNB1
CDK1
CDK2
CDK4
CREBBP
EP300
ESR1
HDAC1
HDAC2
HIST1H1A
HIST1H2AJ
HIST1H2BG
HIST1H4A
HIST2H2BE
HIST2H3C
HIST2H4A
HIST3H3
HSPA1A
IL7R
KEAP1
KPNA2
KPNB1
NCOR1
NUP62
NUPR1
NUTF2
PCNA
PHB2
RAN
RCC1
SET
SIN3A
STAT3
TERF1
TERF2
TERF2IP
VIPR1
ZDHHC17
Entrez ID
8331
5757
HPRD ID
09102
01778
Ensembl ID
ENSG00000187514
Uniprot IDs
Q99878
P06454
Q53S24
PDB IDs
2L9I
Enriched GO Terms of Interacting Partners
?
Chromosome Organization
Chromatin Organization
Organelle Organization
DNA Metabolic Process
Chromatin Modification
Mitotic Cell Cycle
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Telomere Maintenance
Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Histone Modification
DNA Packaging
Regulation Of Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Cell Cycle
Negative Regulation Of Gene Expression, Epigenetic
Response To Organic Substance
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Proliferation
Protein Complex Assembly
Response To Stimulus
Mitotic Cell Cycle Process
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
DNA Replication
Viral Process
DNA Conformation Change
Negative Regulation Of Biosynthetic Process
Homeostatic Process
Regulation Of Protein Metabolic Process
Rhythmic Process
Regulation Of Chromosome Organization
G2/M Transition Of Mitotic Cell Cycle
Cellular Response To Stimulus
Nucleosome Assembly
Regulation Of RNA Metabolic Process
Cell Cycle Process
Cellular Response To Stress
Regulation Of Cell Death
Chromatin Assembly
Tagcloud
?
adjacent
advanced
ajcc
assessment
colon
crc
depth
dfs
distant
help
hence
invasion
lnm
lymph
metastasis
mutant
node
os
overexpression
plays
predict
prognosis
prothymosin
survival
tissue
tp53
translational
triggers
tumorigenesis
Tagcloud (Difference)
?
adjacent
advanced
ajcc
assessment
colon
crc
depth
dfs
distant
help
hence
invasion
lnm
lymph
metastasis
mutant
node
os
overexpression
plays
predict
prognosis
prothymosin
survival
tissue
tp53
translational
triggers
tumorigenesis
Tagcloud (Intersection)
?