TRRAP and MRGBP

Number of citations of the paper that reports this interaction (PMID 12963728)
65

Data Source:
HPRD (in vitro)

		TRRAP	MRGBP
Gene Name		transformation/transcription domain-associated protein	MRG/MORF4L binding protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	PCAF Complex Swr1 Complex Nucleus Nucleoplasm Golgi Apparatus STAGA Complex Transcription Factor TFTC Complex NuA4 Histone Acetyltransferase Complex	Nucleus Nucleoplasm H4/H2A Histone Acetyltransferase Complex
	Molecular Function	Transcription Cofactor Activity Transcription Coactivator Activity Protein Binding Kinase Activity Phosphotransferase Activity, Alcohol Group As Acceptor
	Biological Process	DNA Repair Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Mitotic Cell Cycle Checkpoint Phosphorylation Histone Acetylation Histone Deubiquitination Histone H4 Acetylation Histone H2A Acetylation	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification Regulation Of Growth
Pathways		Chromatin modifying enzymes Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation formation of the beta-catenin:TCF transactivating complex XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer HATs acetylate histones	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ACTL6A ATXN7 BRCA1 BRD8 CTNNB1 E2F1 E2F4 EP400 ESR1 KAT2A MAX MRGBP MYC PYGO2 SKP1 TCF3	17 interactors: ACTB ACTL6A BRD8 DMAP1 ING1 KRTAP10-7 MEAF6 MORF4L1 MORF4L2 MSL1 NOTCH2NL RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4
Entrez ID		8295	55257
HPRD ID		04310	16646
Ensembl ID		ENSG00000196367	ENSG00000101189
Uniprot IDs		Q9Y4A5	A8C4L5 Q9NV56
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Modification Chromatin Organization Organelle Organization Chromosome Organization Histone H4 Acetylation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Histone Acetylation Macromolecule Biosynthetic Process Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Histone H2A Acetylation Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Histone H3-K4 Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Canonical Wnt Signaling Pathway Regulation Of Fibroblast Proliferation Cellular Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cell Proliferation Organ Development Cellular Response To Indole-3-methanol Regulation Of Histone Methylation Tissue Development Chromatin Remodeling Regulation Of Chromosome Organization	Histone H2A Acetylation Histone H4 Acetylation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Chromatin Modification Chromatin Organization Peptidyl-lysine Modification Chromosome Organization Histone Modification Regulation Of Growth Organelle Organization Peptidyl-amino Acid Modification DNA Repair Transcription, DNA-templated Chromatin Remodeling RNA Biosynthetic Process Cellular Response To DNA Damage Stimulus ATP-dependent Chromatin Remodeling DNA Metabolic Process Regulation Of Gene Expression RNA Metabolic Process Cellular Protein Modification Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process Response To Stress Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Response To Stress Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process DNA Recombination Cellular Response To Stimulus Protein Metabolic Process Mitotic Cell Cycle Process Nucleobase-containing Compound Metabolic Process Response To Stimulus Mitotic Cell Cycle Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Ephrin Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		arid1a ash1l atlas broadly chd6 colorectal concordant copy ep300 ep400 exome gains hypermutation mismatch mll2 mll3 nonhypermutated prdm2 preexisting profiled proofreading resembled seq signatures silico srcap tgfbeta uncertain validating
Tagcloud (Difference) ?		arid1a ash1l atlas broadly chd6 colorectal concordant copy ep300 ep400 exome gains hypermutation mismatch mll2 mll3 nonhypermutated prdm2 preexisting profiled proofreading resembled seq signatures silico srcap tgfbeta uncertain validating
Tagcloud (Intersection) ?