CAPNS1 and ATP5J2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CAPNS1	ATP5J2
Gene Name		calpain, small subunit 1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane Extracellular Vesicular Exosome	Nucleus Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Integral Component Of Membrane Proton-transporting ATP Synthase Complex, Coupling Factor F(o) Extracellular Vesicular Exosome
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	ATPase Activity Transmembrane Transporter Activity
	Biological Process	Proteolysis Positive Regulation Of Cell Proliferation Extracellular Matrix Disassembly Extracellular Matrix Organization	Proton Transport Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Degradation of the extracellular matrix	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AGTRAP ARHGEF6 ARR3 ATP5J2 CAPN1 CAPN2 CAST CDK4 DRG1 GET4 GNB2 IL2RG LRRCC1 PPARGC1A RAB1A STAT3 TERF1 TRAF5	13 interactors: ARL8B CAPNS1 CCDC137 CRELD1 FBP1 HAP1 KDM1A LPP NDUFA6 PRPF4 PVRL2 RPLP1 ZFPL1
Entrez ID		826	9551
HPRD ID		00240	16520
Ensembl ID		ENSG00000126247	ENSG00000241468
Uniprot IDs		P04632	P56134
PDB IDs		1KFU 1KFX
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glycolytic Process Signal Transduction Response To Hypoxia Regulation Of Cell Death Cellular Response To Stimulus Signaling Cell Communication Temperature Homeostasis Regulation Of Glycolytic Process Response To Stimulus Regulation Of Apoptotic Process Response To Drug Positive Regulation Of Cell Cycle Process Cellular Response To Nitrite Response To Abiotic Stimulus Positive Regulation Of Cell Cycle Energy Derivation By Oxidation Of Organic Compounds Regulation Of Generation Of Precursor Metabolites And Energy Response To Organic Substance Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Interleukin-7-mediated Signaling Pathway Positive Regulation Of ATP Biosynthetic Process Positive Regulation Of Mitochondrial DNA Metabolic Process Cellular Response To Organic Substance Response To Stress Mitotic Cell Cycle Positive Regulation Of Energy Homeostasis Response To Statin Telomeric Loop Formation Age-dependent Telomere Shortening Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Cell Proliferation Response To Organonitrogen Compound Interleukin-8 Production Telomere Maintenance Via Telomere Shortening Interleukin-2-mediated Signaling Pathway Positive Regulation Of Cellular Respiration Cellular Response To Oxygen Levels Respiratory Electron Transport Chain Response To Amino Acid Generation Of Precursor Metabolites And Energy Positive Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process Cell Division Regulation Of Cell Proliferation Regulation Of Protein Metabolic Process Endomembrane System Organization	Demethylation Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Primitive Erythrocyte Differentiation Coreceptor-mediated Virion Attachment To Host Cell Diencephalon Development Sperm Mitochondrion Organization Susceptibility To T Cell Mediated Cytotoxicity Positive Regulation Of Cilium Assembly Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Fusion Of Virus Membrane With Host Plasma Membrane
Tagcloud ?		afp buffalo cadaveric calpain cd34 curing facilitates fetoprotein greatest hcc hepatectomy hepatoma implantation invasiveness largest lungs microscopic microvessel modalities occult partial project regeneration remnant resection resections sizes transplantation vegfr2	angptl4 atp5d atp5g3 atp5l ccnb1 cdc10 cdc20 cdc23 dyn efemp1 eng epas1 fbn1 fn1 hcaecs hmox1 itga5 itgae itgav lamr1 lgals3 loxl2 lss p4hb pgk1 pkd2 sage vasodilatory vasoreactive
Tagcloud (Difference) ?		afp buffalo cadaveric calpain cd34 curing facilitates fetoprotein greatest hcc hepatectomy hepatoma implantation invasiveness largest lungs microscopic microvessel modalities occult partial project regeneration remnant resection resections sizes transplantation vegfr2	angptl4 atp5d atp5g3 atp5l ccnb1 cdc10 cdc20 cdc23 dyn efemp1 eng epas1 fbn1 fn1 hcaecs hmox1 itga5 itgae itgav lamr1 lgals3 loxl2 lss p4hb pgk1 pkd2 sage vasodilatory vasoreactive
Tagcloud (Intersection) ?