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CAPNS1 and LRRCC1
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
HPRD
(two hybrid)
CAPNS1
LRRCC1
Description
calpain small subunit 1
leucine rich repeat and coiled-coil centrosomal protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Extracellular Exosome
Calpain Complex
Cytoplasm
Centrosome
Centriole
Cytoskeleton
Molecular Function
Calcium-dependent Cysteine-type Endopeptidase Activity
Calcium Ion Binding
Protein Binding
Metal Ion Binding
Biological Process
Proteolysis
Positive Regulation Of Cell Population Proliferation
Regulation Of Macroautophagy
Cell Division
Pathways
Degradation of the extracellular matrix
Degradation of the extracellular matrix
Formation of the cornified envelope
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
Drugs
PD150606
Diseases
GWAS
Metabolite levels (
23823483
)
Interacting Genes
21 interacting genes:
AGTRAP
ARHGEF6
ARR3
ATP5MF
CAPN1
CAPN2
CAST
CDC42
CDK4
DRG1
F2RL1
GET4
GNB2
IL2RG
KCTD7
LRRCC1
PPARGC1A
RAB1A
STAT3
TERF1
TRAF5
4 interacting genes:
C14orf119
CAPNS1
FADD
NRIP1
Entrez ID
826
85444
HPRD ID
00240
11160
Ensembl ID
ENSG00000126247
ENSG00000133739
Uniprot IDs
A0A0C4DGQ5
P04632
B4DTJ0
Q9C099
PDB IDs
1KFU
1KFX
4PHJ
4PHK
4PHM
4WQ2
4WQ3
5D69
6QLB
Enriched GO Terms of Interacting Partners
?
Calpain Complex
Calcium-dependent Cysteine-type Endopeptidase Activity
Positive Regulation Of Pseudopodium Assembly
Positive Regulation Of Endocytosis
Thioesterase Binding
Positive Regulation Of Phagocytosis
Positive Regulation Of Interleukin-8 Production
Interleukin-15-mediated Signaling Pathway
Interleukin-2-mediated Signaling Pathway
Interleukin-9-mediated Signaling Pathway
Cytosol
Pseudopodium
Regulation Of Interleukin-8 Production
Cytoplasm
Positive Regulation Of Cellular Component Organization
Regulation Of Phagocytosis
GTPase Activity
Regulation Of Endocytosis
LncRNA Binding
Regulation Of Interleukin-6 Production
Calcium-dependent Cysteine-type Endopeptidase Inhibitor Activity
Positive Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
Establishment Of Endothelial Barrier
Positive Regulation Of Interleukin-10 Production
Endothelial Cell Development
Positive Regulation Of Renin Secretion Into Blood Stream
Signal Transduction Involved In Regulation Of Gene Expression
Temperature Homeostasis
Negative Regulation Of Establishment Of Protein Localization To Telomere
Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
Negative Regulation Of Establishment Of RNA Localization To Telomere
Positive Regulation Of Shelterin Complex Assembly
Calpain Complex
Ovarian Follicle Rupture
Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation
Ripoptosome
Positive Regulation Of T Cell Extravasation
Death Effector Domain Binding
Receptor Serine/threonine Kinase Binding
Negative Regulation Of Activation-induced Cell Death Of T Cells
Regulation Of Activation-induced Cell Death Of T Cells
Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation
CD95 Death-inducing Signaling Complex
Death-inducing Signaling Complex Assembly
Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation
Death-inducing Signaling Complex
Tumor Necrosis Factor Receptor Superfamily Binding
Necroptotic Signaling Pathway
TRAIL-activated Apoptotic Signaling Pathway
Calcium-dependent Cysteine-type Endopeptidase Activity
Nuclear Retinoid X Receptor Binding
Ovulation
Nuclear Glucocorticoid Receptor Binding
Nuclear Retinoic Acid Receptor Binding
Positive Regulation Of Macrophage Differentiation
Positive Regulation Of Cellular Extravasation
Death Receptor Binding
Behavioral Response To Cocaine
Motor Neuron Apoptotic Process
Caspase Binding
Positive Regulation Of Type I Interferon-mediated Signaling Pathway
Negative Regulation Of Necroptotic Process
Lymph Node Development
Positive Regulation Of Execution Phase Of Apoptosis
Negative Regulation Of Programmed Necrotic Cell Death
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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