TNS1 and KLF10

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TNS1	KLF10
Gene Name		tensin 1	Kruppel-like factor 10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Focal Adhesion Cell Surface	Nucleus
	Molecular Function	Actin Binding Protein Binding Poly(A) RNA Binding	Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Cell-substrate Junction Assembly Fibroblast Migration	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Transcription, DNA-templated Transforming Growth Factor Beta Receptor Signaling Pathway Cell-cell Signaling Circadian Rhythm Cell Proliferation Negative Regulation Of Cell Proliferation Cellular Response To Starvation Bone Mineralization Somatic Stem Cell Maintenance Regulation Of Circadian Rhythm Positive Regulation Of Osteoclast Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Peptide
Pathways
Drugs
Diseases
GWAS		Height ( 21998595 20881960) Pulmonary function ( 20010834) Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		6 interactors: CAPN2 KLF10 OSGEP PPP1CC PTK2 YWHAZ	13 interactors: BOP1 CDK6 CRIP2 KAT2B LENG1 LRRC75A-AS1 PIGC RPL14 SF3B3 SIN3A SP1 TNS1 ZNF512B
Entrez ID		7145	7071
HPRD ID		02512	03527
Ensembl ID		ENSG00000079308	ENSG00000155090
Uniprot IDs		A1L0S7 E9PGF5 Q59G71 Q86VB0 Q9HBL0	Q13118
PDB IDs			2EPA
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Response To Organonitrogen Compound Regulation Of Circadian Rhythm Cellular Response To Growth Factor Stimulus Response To Growth Factor Threonylcarbamoyladenosine Biosynthetic Process Cellular Response To Organic Substance Circadian Rhythm Response To Organonitrogen Compound Netrin-activated Signaling Pathway Golgi Reassembly Platelet Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Organelle Organization Threonylcarbamoyladenosine Metabolic Process Histamine Secretion By Mast Cell Negative Regulation Of Synapse Assembly Response To Organic Substance Establishment Of Golgi Localization Signal Complex Assembly Golgi Inheritance Histamine Secretion Rhythmic Process Protein Autoprocessing Establishment Of Organelle Localization Cellular Response To Peptide Histamine Transport Golgi Localization Adenosine Metabolic Process Negative Regulation Of Anoikis Organelle Localization Establishment Of Nucleus Localization Blood Coagulation Regulation Of Anoikis Hemostasis Mast Cell Degranulation Response To Stress Production Of Molecular Mediator Involved In Inflammatory Response Triglyceride Catabolic Process Myoblast Fusion Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Response To Peptide Mast Cell Mediated Immunity Cellular Metabolic Process Growth Hormone Receptor Signaling Pathway Regulation Of Cytoskeleton Organization	Hematopoietic Progenitor Cell Differentiation Ribosomal Large Subunit Biogenesis Hemopoiesis Immune System Development RNA Metabolic Process Rhythmic Process Response To Methylglyoxal Sequestering Of Nodal From Receptor Via Nodal Binding Cell Dedifferentiation Negative Regulation Of Histone H3-K27 Acetylation Regulation Of Cell Cycle Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Negative Regulation Of Nodal Signaling Pathway Cleavage In ITS2 Between 5.8S RRNA And LSU-rRNA Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Chromatin Silencing RRNA Processing RRNA Metabolic Process Notch Signaling Pathway Viral Process Cell Cycle Arrest Determination Of Left/right Asymmetry In Lateral Mesoderm Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Nodal Signaling Pathway Positive Regulation Of Gluconeogenesis By Positive Regulation Of Transcription From RNA Polymerase II Promoter Maturation Of LSU-rRNA Gene Expression Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Sequestering Of Extracellular Ligand From Receptor Ribosome Biogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Negative Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Cellular Senescence Cellular Nitrogen Compound Metabolic Process Positive Regulation By Host Of Viral Transcription Fibroblast Migration Regulation Of Protein Glycosylation Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Embryonic Process Involved In Female Pregnancy DNA-templated Transcription, Initiation N-terminal Protein Amino Acid Acetylation Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Tagcloud ?		aberration aberrations algorithms cgh characterised cin coca confirms crc custom deleted deletions driver fmcr gained gains hybridisation ifnar1 ifnar2 kcnma1 microsatellite mss nfkbia oncogenes prdm16 rassf3 rpa3 scna silico	acetyltransferase advance antagonistic associate characterize epigenetically foxp3 indeed inducibility inherited integrate integrated interacting kruppel modifying nh2 pcaf physically recapitulated reciprocal renders reporter repressor sin3 studying toggle underlie underlies works
Tagcloud (Difference) ?		aberration aberrations algorithms cgh characterised cin coca confirms crc custom deleted deletions driver fmcr gained gains hybridisation ifnar1 ifnar2 kcnma1 microsatellite mss nfkbia oncogenes prdm16 rassf3 rpa3 scna silico	acetyltransferase advance antagonistic associate characterize epigenetically foxp3 indeed inducibility inherited integrate integrated interacting kruppel modifying nh2 pcaf physically recapitulated reciprocal renders reporter repressor sin3 studying toggle underlie underlies works
Tagcloud (Intersection) ?