CLTCL1 and SNX5

Number of citations of the paper that reports this interaction (PMID 15133132)
16

Data Source:
HPRD (two hybrid, in vivo)

		CLTCL1	SNX5
Gene Name		clathrin, heavy chain-like 1	sorting nexin 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Spindle Coated Pit Membrane Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Coated Vesicle Clathrin-coated Vesicle Extracellular Vesicular Exosome	Ruffle Phagocytic Cup Cytoplasmic Vesicle Membrane Retromer Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extrinsic Component Of Endosome Membrane Early Endosome Membrane Macropinocytic Cup Tubular Endosome
	Molecular Function	Signal Transducer Activity Structural Molecule Activity Protein Binding	Protein Binding Dynactin Binding Phosphatidylinositol Binding
	Biological Process	Intracellular Protein Transport Receptor-mediated Endocytosis Mitotic Nuclear Division Signal Transduction Anatomical Structure Morphogenesis Positive Regulation Of Glucose Import	Intracellular Protein Transport Pinocytosis Vesicle Organization Retrograde Transport, Endosome To Golgi
Pathways		Formation of annular gap junctions EPH-ephrin mediated repulsion of cells Axon guidance Gap junction degradation Gap junction trafficking and regulation Gap junction trafficking EPH-Ephrin signaling	Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Metabolite levels ( 22916037)
Protein-Protein Interactions		3 interactors: EGFR PICALM SNX5	14 interactors: APPBP2 CDC37 CLTC CLTCL1 DNAJB11 FANCA HGS HMOX2 ITSN1 MESDC2 MIB1 PFDN1 PRKRA SNX2
Entrez ID		8218	27131
HPRD ID		03172	10439
Ensembl ID		ENSG00000070371	ENSG00000089006
Uniprot IDs		P53675	Q6P5V6 Q9Y5X3
PDB IDs			1SYS
Enriched GO Terms of Interacting Partners?		Alkanesulfonate Metabolic Process Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Vesicle Organization Endosomal Transport Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Activation Of Phospholipase A2 Activity Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Positive Regulation Of Phospholipase A2 Activity Response To Cobalamin Response To UV-A Cargo Loading Into Vesicle Iron Ion Import Into Cell Response To Hydroxyisoflavone Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Cellular Localization Metal Ion Homeostasis Positive Regulation Of Catenin Import Into Nucleus Synaptic Vesicle Maturation Positive Regulation Of Beta-amyloid Formation Regulation Of Phospholipase A2 Activity Negative Regulation Of Amyloid Precursor Protein Catabolic Process Axonogenesis Regulation Of Superoxide Anion Generation Pinocytosis Ion Homeostasis Axon Development Iron Ion Import Cell Morphogenesis Involved In Neuron Differentiation Magnesium Ion Homeostasis Neuron Projection Morphogenesis Endocytosis Cellular Response To Estradiol Stimulus Regulation Of Beta-amyloid Formation Negative Regulation Of Receptor-mediated Endocytosis Protein Insertion Into Membrane Astrocyte Development Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Cell Morphogenesis Involved In Differentiation Cell Proliferation Regulation Of Catenin Import Into Nucleus Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Protein Localization Clathrin Coat Assembly Response To Epidermal Growth Factor Neuron Projection Development	Cellular Protein Localization Intracellular Protein Transport Cellular Localization Protein Folding Endocytosis Protein Localization Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization Intracellular Transport Transport Vesicle-mediated Transport Developmental Process Negative Regulation Of Hyaluronan Biosynthetic Process Heme Oxidation Anatomical Structure Development Lamellipodium Morphogenesis
Tagcloud ?			counteracted egf egfr endosomal endosomes escrt generating ilvs intraluminal laptm4b lysosomal machineries mves neutralizes oncoprotein p2 pip pipkigammai5 promoting ptdins recruiting sorting termination transform transmembrane ubiquitinated ubiquitination vesicles vesicular
Tagcloud (Difference) ?			counteracted egf egfr endosomal endosomes escrt generating ilvs intraluminal laptm4b lysosomal machineries mves neutralizes oncoprotein p2 pip pipkigammai5 promoting ptdins recruiting sorting termination transform transmembrane ubiquitinated ubiquitination vesicles vesicular
Tagcloud (Intersection) ?