CLTCL1

Gene Name		clathrin, heavy chain-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Spindle Coated Pit Membrane Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Coated Vesicle Clathrin-coated Vesicle Extracellular Vesicular Exosome
	Molecular Function	Signal Transducer Activity Structural Molecule Activity Protein Binding
	Biological Process	Intracellular Protein Transport Receptor-mediated Endocytosis Mitotic Nuclear Division Signal Transduction Anatomical Structure Morphogenesis Positive Regulation Of Glucose Import
Pathways		Formation of annular gap junctions EPH-ephrin mediated repulsion of cells Axon guidance Gap junction degradation Gap junction trafficking and regulation Gap junction trafficking EPH-Ephrin signaling
Drugs
Diseases
GWAS		Metabolite levels ( 22916037)
Protein-protein Interactions		3 interactors: EGFR PICALM SNX5
Entrez ID		8218
HPRD ID		03172
Ensembl ID		ENSG00000070371
Uniprot IDs		P53675
PDB IDs
Enriched GO Terms of Interacting Partners?		Alkanesulfonate Metabolic Process Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Vesicle Organization Endosomal Transport Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Activation Of Phospholipase A2 Activity Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Positive Regulation Of Phospholipase A2 Activity Response To Cobalamin Response To UV-A Cargo Loading Into Vesicle Iron Ion Import Into Cell Response To Hydroxyisoflavone Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Cellular Localization Metal Ion Homeostasis Positive Regulation Of Catenin Import Into Nucleus Synaptic Vesicle Maturation Positive Regulation Of Beta-amyloid Formation Regulation Of Phospholipase A2 Activity Negative Regulation Of Amyloid Precursor Protein Catabolic Process Axonogenesis Regulation Of Superoxide Anion Generation Pinocytosis Ion Homeostasis Axon Development Iron Ion Import Cell Morphogenesis Involved In Neuron Differentiation Magnesium Ion Homeostasis Neuron Projection Morphogenesis Endocytosis Cellular Response To Estradiol Stimulus Regulation Of Beta-amyloid Formation Negative Regulation Of Receptor-mediated Endocytosis Protein Insertion Into Membrane Astrocyte Development Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Cell Morphogenesis Involved In Differentiation Cell Proliferation Regulation Of Catenin Import Into Nucleus Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Protein Localization Clathrin Coat Assembly Response To Epidermal Growth Factor Neuron Projection Development
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