ABHD17A and RGS20

Number of citations of the paper that reports this interaction (PubMedID 21516116)
20

Data Source:
BioGRID (two hybrid)

		ABHD17A	RGS20
Description		abhydrolase domain containing 17A, depalmitoylase	regulator of G protein signaling 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Endosome Membrane Postsynaptic Density Membrane Nuclear Speck Cell Projection Dendritic Spine Synapse Postsynaptic Membrane Recycling Endosome Membrane Postsynaptic Density Membrane Postsynaptic Recycling Endosome Membrane Glutamatergic Synapse	Nucleus Cytoplasm Trans-Golgi Network Plasma Membrane Membrane
	Molecular Function	Protein Binding Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Protein Depalmitoylation NLRP3 Inflammasome Complex Assembly Protein Localization To Membrane Regulation Of Postsynapse Organization Negative Regulation Of NLRP3 Inflammasome Complex Assembly Positive Regulation Of NLRP3 Inflammasome Complex Assembly Negative Regulation Of Protein Localization To Microtubule Positive Regulation Of Protein Localization To Endosome	G Protein-coupled Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction
Pathways		RAS processing	G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS			Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Chronic obstructive pulmonary disease ( 32222710) Serum uric acid levels ( 29559957) Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		14 interacting genes: BIRC2 DLG4 EHMT2 GOLGA2 GPC4 HPGDS KRTAP5-9 MDFI PLSCR4 PNMA1 RGS20 TNIP1 TRAF1 TRIM27	58 interacting genes: ABHD17A ADRB2 ALPP AQP1 CATSPER1 COL8A1 CRCT1 CREB5 FASLG GLRX3 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ HOXA1 HRG HSPD1 INS KIF1A KLHL38 KRTAP4-2 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 MAPKBP1 NECTIN2 NECTIN3 NEK8 NUFIP2 OSTM1 OTX1 PTGER3 PTPMT1 RANBP3 STMN2 TBC1D16 VASN
Entrez ID		81926	8601
HPRD ID		07475	06225
Ensembl ID		ENSG00000129968	ENSG00000147509
Uniprot IDs		Q96GS6	B3KSW4 H9NIM5 O76081
PDB IDs
Enriched GO Terms of Interacting Partners?			Keratinization Epidermis Development Tissue Development Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Binding Intermediate Filament Heterotrimeric G-protein Complex Identical Protein Binding Protein Binding Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Secretion Positive Regulation Of Immune Response To Tumor Cell G Protein-coupled Serotonin Receptor Signaling Pathway Neuronal Dense Core Vesicle Adenylate Cyclase Inhibitor Activity Adenylate Cyclase Regulator Activity G Protein-coupled Receptor Binding Negative Regulation Of Protein Secretion Regulation Of Response To Tumor Cell Negative Regulation Of Secretion By Cell Negative Regulation Of Insulin Secretion Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Negative Regulation Of Peptide Secretion Hippocampal Mossy Fiber To CA3 Synapse Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Protein Transport Negative Regulation Of Protein Localization Developmental Process Adhesion Of Symbiont To Host
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