Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
ABHD17A and HPGDS
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
ABHD17A
HPGDS
Gene Name
abhydrolase domain containing 17A
hematopoietic prostaglandin D synthase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Membrane
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Hydrolase Activity
Magnesium Ion Binding
Glutathione Transferase Activity
Prostaglandin-D Synthase Activity
Calcium Ion Binding
Protein Homodimerization Activity
Biological Process
Biological_process
Metabolic Process
Prostaglandin Metabolic Process
Xenobiotic Metabolic Process
Signal Transduction
Locomotory Behavior
Arachidonic Acid Metabolic Process
Cyclooxygenase Pathway
Small Molecule Metabolic Process
Glutathione Derivative Biosynthetic Process
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Metabolism of lipids and lipoproteins
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective UGT1A4 causes hyperbilirubinemia
Glutathione conjugation
Metabolic disorders of biological oxidation enzymes
Arachidonic acid metabolism
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Glutathione
2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride
Glycerol
3-phenyl-5-(1H-pyrazol-3-yl)isoxazole
PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE
2-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid
4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid
4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE
nocodazole
3-(4-nitrophenyl)-1H-pyrazole
1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
Diseases
GWAS
Testicular germ cell tumor (
23666239
)
Protein-Protein Interactions
2 interactors:
HOXA1
HPGDS
4 interactors:
ABHD17A
ARRDC3
HK3
MFI2
Entrez ID
81926
27306
HPRD ID
07475
04001
Ensembl ID
ENSG00000129968
ENSG00000163106
Uniprot IDs
Q96GS6
O60760
PDB IDs
1IYH
1IYI
1V40
2CVD
2VCQ
2VCW
2VCX
2VCZ
2VD0
2VD1
3EE2
3KXO
3VI5
3VI7
4EC0
4EDY
4EDZ
4EE0
Enriched GO Terms of Interacting Partners
?
Optokinetic Behavior
Abducens Nerve Formation
Facial Nucleus Development
Semicircular Canal Formation
Rhombomere 4 Development
Rhombomere 3 Development
Rhombomere 5 Development
Behavior
Embryonic Neurocranium Morphogenesis
Outer Ear Morphogenesis
Semicircular Canal Morphogenesis
Rhombomere Development
Facial Nerve Structural Organization
Pons Development
Facial Nerve Morphogenesis
Semicircular Canal Development
Cyclooxygenase Pathway
Parasympathetic Nervous System Development
Anatomical Structure Arrangement
Prostaglandin Biosynthetic Process
Glutathione Derivative Biosynthetic Process
Cochlea Morphogenesis
Prostaglandin Metabolic Process
Motor Neuron Axon Guidance
Autonomic Nervous System Development
Icosanoid Biosynthetic Process
Cochlea Development
Neural Nucleus Development
Cranial Nerve Development
Unsaturated Fatty Acid Biosynthetic Process
Artery Morphogenesis
Arachidonic Acid Metabolic Process
Visual Behavior
Artery Development
Embryonic Cranial Skeleton Morphogenesis
Cellular Response To Retinoic Acid
Nerve Development
Icosanoid Metabolic Process
Inner Ear Morphogenesis
Unsaturated Fatty Acid Metabolic Process
Long-chain Fatty Acid Metabolic Process
Ear Morphogenesis
Response To Retinoic Acid
Embryonic Skeletal System Morphogenesis
Metencephalon Development
Neuromuscular Process
Fatty Acid Biosynthetic Process
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Response To Xenobiotic Stimulus
Negative Regulation Of Locomotion Involved In Locomotory Behavior
Negative Regulation Of Heat Generation
Positive Regulation Of Adrenergic Receptor Signaling Pathway
Regulation Of Locomotion Involved In Locomotory Behavior
Positive Regulation Of Extracellular Matrix Disassembly
Homeostatic Process
Positive Regulation Of Plasminogen Activation
Regulation Of Adrenergic Receptor Signaling Pathway
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Fat Pad Development
Negative Regulation Of Multicellular Organismal Metabolic Process
Iron Ion Import
Cellular Chemical Homeostasis
Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Positive Regulation Of Protein Processing
Temperature Homeostasis
Cellular Homeostasis
Regulation Of Extracellular Matrix Disassembly
Regulation Of Substrate Adhesion-dependent Cell Spreading
Glucose 6-phosphate Metabolic Process
Adipose Tissue Development
Regulation Of Extracellular Matrix Organization
Chemical Homeostasis
Negative Regulation Of Cell-substrate Adhesion
Carbohydrate Phosphorylation
Glucose Transport
Positive Regulation Of Ubiquitin-protein Transferase Activity
Cellular Glucose Homeostasis
Positive Regulation Of Ligase Activity
Hexose Transport
Iron Ion Transport
Tagcloud
?
11beta
9alpha
abcc4
akr1b1
akr1c1
akr1c3
catalyze
diseased
endometriosis
endometriotic
endometrium
gynecological
hieec
hiesc
infertility
peritoneal
pgd2
pgf2alpha
pgh2
pla2g2a
pla2g4a
provokes
ptgds
ptgfr
ptgs2
reaches
slco2a
synthases
Tagcloud (Difference)
?
11beta
9alpha
abcc4
akr1b1
akr1c1
akr1c3
catalyze
diseased
endometriosis
endometriotic
endometrium
gynecological
hieec
hiesc
infertility
peritoneal
pgd2
pgf2alpha
pgh2
pla2g2a
pla2g4a
provokes
ptgds
ptgfr
ptgs2
reaches
slco2a
synthases
Tagcloud (Intersection)
?