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MAPKBP1 and TCF4
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
MAPKBP1
TCF4
Gene Name
mitogen-activated protein kinase binding protein 1
transcription factor 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Transcription Factor Complex
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
Sequence-specific DNA Binding RNA Polymerase Recruiting Transcription Factor Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
TFIIB-class Binding Transcription Factor Activity
TFIIB-class Transcription Factor Binding
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Protein C-terminus Binding
Protein Heterodimerization Activity
E-box Binding
Biological Process
DNA-templated Transcription, Initiation
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein-DNA Complex Assembly
Pathways
CDO in myogenesis
Myogenesis
Drugs
Diseases
GWAS
Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) (
23453885
)
Diabetic retinopathy (
21441570
)
Fuchs's corneal dystrophy (
20825314
)
Obesity (early onset extreme) (
23563609
)
Schizophrenia (
21926974
19571808
19571811
22688191
23894747
)
Sclerosing cholangitis and ulcerative colitis (combined) (
22821403
)
Protein-Protein Interactions
31 interactors:
ADAMTSL4
ALG13
APTX
GLRX3
KEAP1
KRT31
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP3-2
KRTAP4-12
KRTAP5-9
KRTAP9-2
KRTAP9-4
MAPK10
MAPK8
MAPK9
MDFI
MEOX2
NOTCH2NL
RGS20
SIAH1
SPRY2
TCF12
TCF4
TEX11
TRIM27
TRIP6
173 interactors:
AES
AQP1
AR
ARHGEF1
ARMC7
ASCL1
ASCL3
ASCL4
ASPSCR1
ATP6V1B2
BCAS2
BCL2L2
BZRAP1
C19orf66
C1orf109
C9orf171
CABP5
CALM1
CALM2
CALM3
CCDC101
CDC73
CDKN1A
CDKN2C
CHAF1A
CHCHD2
CHIC2
CKS1B
CTBP1
CTNNB1
DDX6
DEF6
DGCR6
DMRT3
EFHC1
EIF4E2
EIF4EBP1
EP300
EPB41L3
EPHB6
EXOSC1
FAH
FAM124B
FAM74A4
FERD3L
FLAD1
FLNA
FRS3
GEM
GLRX3
GNG10
GOLGA8EP
GOLGA8F
GORASP2
GTF3C5
GUCD1
HAND2
HAT1
HBP1
HIC1
HSPB7
ID1
ID2
ID3
ID4
INS
JUN
JUP
KCTD14
KLC3
KLHL32
LASP1
LENG1
LGALS14
LMO1
LMO4
LNPEP
LYL1
MAD2L2
MAGOHB
MAPKBP1
MATN3
MEMO1
MEN1
MLLT6
MORN4
MRFAP1L1
MRPL10
MSC
MSRB3
MVP
MYO5B
MYOD1
NCK2
NDOR1
NEK6
NEK8
NEU4
NEUROD1
NEUROG1
NME7
NMUR2
NOL9
NR2C2AP
NR4A1
NUDT10
ORC4
OSGIN1
OTUD4
PARK2
PARP1
PATE1
PBLD
PIN1
PLEKHN1
POLR1A
POLR1C
PPIA
PPIL1
PPP1R18
PRKAA2
PRKAB2
PSEN1
PSMA1
PSMG2
PTF1A
PTGER3
RAB41
RABIF
RECK
RELA
REXO1L6P
RNF138
RSPH14
RUNX1T1
SCOC
SEC14L4
SIGLEC6
SLC39A13
SLC4A1AP
SMCP
SMOC1
SPATC1L
SPG21
SRSF2
STAMBPL1
STK16
STX11
SUMO1
SZT2
TAL1
TAL2
TAPBPL
TCEA2
TCF3
TCL1A
TLE1
TMEM213
TRAPPC2L
TSSC4
TSSK3
TWIST2
TXNL4B
USP4
UTP23
VPS28
XRCC5
XRCC6
ZDHHC24
ZNF124
ZNF205-AS1
ZNF417
ZNF587
Entrez ID
23005
6925
HPRD ID
17465
03780
Ensembl ID
ENSG00000137802
ENSG00000196628
Uniprot IDs
O60336
B3KVA4
E9PH57
H3BTP3
P15884
PDB IDs
2KWF
Enriched GO Terms of Interacting Partners
?
JUN Phosphorylation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
JNK Cascade
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
MAPK Cascade
Regulation Of Gene Expression
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Circadian Rhythm
Signal Transduction By Phosphorylation
Toll-like Receptor Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Apoptotic Process
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Regulation Of Cell Death
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Metabolic Process
Activation Of Innate Immune Response
Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Intracellular Signal Transduction
Regulation Of Protein Localization
Regulation Of Intracellular Transport
Positive Regulation Of Innate Immune Response
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Signaling
Positive Regulation Of Apoptotic Signaling Pathway
Developmental Process
Regulation Of Nucleocytoplasmic Transport
Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Fc-epsilon Receptor Signaling Pathway
Gene Expression
Transcription, DNA-templated
RNA Metabolic Process
RNA Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Cell Cycle
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of DNA Binding
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Multicellular Organismal Development
Negative Regulation Of Cellular Protein Metabolic Process
Organ Development
Regulation Of Metabolic Process
Regulation Of Binding
System Development
Regulation Of Nitrogen Compound Metabolic Process
Developmental Process
Regulation Of Gene Expression
Central Nervous System Development
Anatomical Structure Development
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of DNA Binding
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Organic Substance
Positive Regulation Of Macromolecule Biosynthetic Process
Cell Fate Commitment
Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud
?
action
activities
agent
beta
biejiajian
catenin
cultured
cyclin
cytoplasmic
d1
downstream
expressions
fed
hepatocellular
hepg2
immunofluorescence
inhibiting
invasiveness
lowered
luciferase
mmp
pills
qrt
sera
serve
suppress
underlying
whose
wnt
Tagcloud (Difference)
?
action
activities
agent
beta
biejiajian
catenin
cultured
cyclin
cytoplasmic
d1
downstream
expressions
fed
hepatocellular
hepg2
immunofluorescence
inhibiting
invasiveness
lowered
luciferase
mmp
pills
qrt
sera
serve
suppress
underlying
whose
wnt
Tagcloud (Intersection)
?