UNC93B1 and MBOAT7

Number of citations of the paper that reports this interaction (PMID 21903422)
33

Data Source:
BioGRID (pull down)

		UNC93B1	MBOAT7
Gene Name		unc-93 homolog B1 (C. elegans)	membrane bound O-acyltransferase domain containing 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Toll-like Receptor Binding	Protein Binding Lysophospholipid Acyltransferase Activity
	Biological Process	Toll-like Receptor Signaling Pathway Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus	Phospholipid Metabolic Process Ventricular System Development Layer Formation In Cerebral Cortex Phosphatidylinositol Acyl-chain Remodeling Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways		Toll-Like Receptors Cascades Trafficking and processing of endosomal TLR Innate Immune System	Metabolism of lipids and lipoproteins Acyl chain remodelling of PI Phospholipid metabolism Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: CLPTM1 IRAK1 MBOAT7 SURF4	3 interactors: MAPK6 TMEM173 UNC93B1
Entrez ID		81622	79143
HPRD ID		12191	06925
Ensembl ID		ENSG00000110057	ENSG00000125505
Uniprot IDs		Q05BS6 Q58F16 Q9H1C4	Q96N66
PDB IDs
Enriched GO Terms of Interacting Partners?			Activation Of Innate Immune Response Defense Response To Virus Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Toll-like Receptor 7 Signaling Pathway Response To Virus Interferon-beta Production Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Import Into Nucleus, Translocation Cellular Response To Interferon-beta Type I Interferon Production Positive Regulation Of Defense Response To Virus By Host Positive Regulation Of Immune Response Regulation Of Protein Import Into Nucleus, Translocation Response To Interferon-beta Response To Other Organism Response To Biotic Stimulus Innate Immune Response Regulation Of Defense Response To Virus By Host Regulation Of Immune Response Positive Regulation Of Immune System Process Cellular Response To DsRNA Positive Regulation Of Transcription Factor Import Into Nucleus Response To Exogenous DsRNA Toll-like Receptor 9 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Binding Immune Response Regulation Of Immune System Process Defense Response Response To DsRNA Positive Regulation Of Type I Interferon Production Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Binding Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To External Stimulus Cytokine Production
Tagcloud ?		assisted cal cct cpg dendritic endolysosomes endoplasmic feedback injured odn oligodeoxynucleotide pathogen plasmacytoid released repeats rescue restraining reticulum sat05f selectively sense sirs tlr7 tlr9 toll trafficking transmembrane trauma valuable
Tagcloud (Difference) ?		assisted cal cct cpg dendritic endolysosomes endoplasmic feedback injured odn oligodeoxynucleotide pathogen plasmacytoid released repeats rescue restraining reticulum sat05f selectively sense sirs tlr7 tlr9 toll trafficking transmembrane trauma valuable
Tagcloud (Intersection) ?