MBOAT7 and UNC93B1

Number of citations of the paper that reports this interaction (PMID 21903422)
33

Data Source:
BioGRID (pull down)

		MBOAT7	UNC93B1
Gene Name		membrane bound O-acyltransferase domain containing 7	unc-93 homolog B1 (C. elegans)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome
	Molecular Function	Protein Binding Lysophospholipid Acyltransferase Activity	Toll-like Receptor Binding
	Biological Process	Phospholipid Metabolic Process Ventricular System Development Layer Formation In Cerebral Cortex Phosphatidylinositol Acyl-chain Remodeling Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	Toll-like Receptor Signaling Pathway Intracellular Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways		Metabolism of lipids and lipoproteins Acyl chain remodelling of PI Phospholipid metabolism Glycerophospholipid biosynthesis	Toll-Like Receptors Cascades Trafficking and processing of endosomal TLR Innate Immune System
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: MAPK6 TMEM173 UNC93B1	4 interactors: CLPTM1 IRAK1 MBOAT7 SURF4
Entrez ID		79143	81622
HPRD ID		06925	12191
Ensembl ID		ENSG00000125505	ENSG00000110057
Uniprot IDs		Q96N66	Q05BS6 Q58F16 Q9H1C4
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of Innate Immune Response Defense Response To Virus Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Toll-like Receptor 7 Signaling Pathway Response To Virus Interferon-beta Production Cellular Response To Exogenous DsRNA Positive Regulation Of Protein Import Into Nucleus, Translocation Cellular Response To Interferon-beta Type I Interferon Production Positive Regulation Of Defense Response To Virus By Host Positive Regulation Of Immune Response Regulation Of Protein Import Into Nucleus, Translocation Response To Interferon-beta Response To Other Organism Response To Biotic Stimulus Innate Immune Response Regulation Of Defense Response To Virus By Host Regulation Of Immune Response Positive Regulation Of Immune System Process Cellular Response To DsRNA Positive Regulation Of Transcription Factor Import Into Nucleus Response To Exogenous DsRNA Toll-like Receptor 9 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Binding Immune Response Regulation Of Immune System Process Defense Response Response To DsRNA Positive Regulation Of Type I Interferon Production Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Binding Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To External Stimulus Cytokine Production
Tagcloud ?			assisted cal cct cpg dendritic endolysosomes endoplasmic feedback injured odn oligodeoxynucleotide pathogen plasmacytoid released repeats rescue restraining reticulum sat05f selectively sense sirs tlr7 tlr9 toll trafficking transmembrane trauma valuable
Tagcloud (Difference) ?			assisted cal cct cpg dendritic endolysosomes endoplasmic feedback injured odn oligodeoxynucleotide pathogen plasmacytoid released repeats rescue restraining reticulum sat05f selectively sense sirs tlr7 tlr9 toll trafficking transmembrane trauma valuable
Tagcloud (Intersection) ?