FRMD4A and TRAF3IP1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		FRMD4A	TRAF3IP1
Gene Name		FERM domain containing 4A	TNF receptor-associated factor 3 interacting protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Tight Junction	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Primary Cilium Ciliary Tip
	Molecular Function	Protein Binding, Bridging	Protein Binding Microtubule Binding
	Biological Process	Establishment Of Epithelial Cell Polarity	Organelle Organization Neural Tube Patterning Embryonic Camera-type Eye Development Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Post-anal Tail Morphogenesis Intraciliary Transport Cilium Assembly Embryonic Digit Morphogenesis Negative Regulation Of Defense Response To Virus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS		Alzheimer's disease ( 22430674) RR interval (heart rate) ( 20031603)	Iris characteristics ( 21835309)
Protein-Protein Interactions		2 interactors: TRAF3IP1 YEATS4	27 interactors: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 WAC
Entrez ID		55691	26146
HPRD ID		13553	09571
Ensembl ID		ENSG00000151474	ENSG00000204104
Uniprot IDs		Q9P2Q2	Q8TDR0
PDB IDs			2EQO
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Negative Regulation Of Interferon-beta Production Histone H2A Acetylation	Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Cell Cycle Process Golgi To Plasma Membrane Protein Transport Meiotic Chromosome Condensation Cell Cycle Golgi Vesicle Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Generation Of Neurons TRIF-dependent Toll-like Receptor Signaling Pathway Neurogenesis Organelle Organization MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Signaling Cell Communication Mitotic Sister Chromatid Segregation Cell Division Establishment Of Protein Localization To Plasma Membrane Regulation Of Neurogenesis Toll-like Receptor 4 Signaling Pathway Nervous System Development Negative Regulation Of Cell Cycle Vesicle-mediated Transport Sister Chromatid Segregation Movement Of Cell Or Subcellular Component Cellular Localization Mitochondrial Calcium Ion Homeostasis Regulation Of Cell Differentiation Toll-like Receptor Signaling Pathway Membrane Organization Regulation Of Cell Development Regulation Of Neuron Differentiation Kinetochore Organization Mitotic Nuclear Division Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Protein Metabolic Process Mitotic Chromosome Condensation Pattern Recognition Receptor Signaling Pathway Regulation Of Cell Cycle Innate Immune Response-activating Signal Transduction Cellular Response To Stimulus Response To Stimulus Activation Of Innate Immune Response Signal Transduction Cell Differentiation Protein Localization To Plasma Membrane DNA Damage Checkpoint Regulation Of Neuron Projection Development
Tagcloud ?		amyloidogenic beta40 beta42 bin1 biopsies braak categorized cerebrospinal clu dichotomized displays exons grouped hydrocephalus idiopathic inferior mechanistic ms4a6a neurofibrillary pathology postmortem relation responding secretase shunt splicing trait trem2 vi	13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral
Tagcloud (Difference) ?		amyloidogenic beta40 beta42 bin1 biopsies braak categorized cerebrospinal clu dichotomized displays exons grouped hydrocephalus idiopathic inferior mechanistic ms4a6a neurofibrillary pathology postmortem relation responding secretase shunt splicing trait trem2 vi	13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral
Tagcloud (Intersection) ?