FRMD4A and TRAF3IP1

Number of citations of the paper that reports this interaction (PubMedID 17043677)
0

Data Source:
BioGRID (two hybrid)

		FRMD4A	TRAF3IP1
Description		FERM domain containing 4A	TRAF3 interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Adherens Junction Bicellular Tight Junction Anchoring Junction	Fibrillar Center Nucleoplasm Cytoplasm Centrosome Cytoskeleton Cilium Axoneme Nuclear Body Intraciliary Transport Particle B Ciliary Transition Zone Ciliary Basal Body Cell Projection Ciliary Tip Ciliary Base
	Molecular Function	Protein-macromolecule Adaptor Activity	Protein Binding Microtubule Binding
	Biological Process	Negative Regulation Of Protein Secretion Positive Regulation Of Protein Secretion Establishment Of Epithelial Cell Polarity	Morphogenesis Of A Polarized Epithelium Kidney Development Negative Regulation Of Protein Phosphorylation Neural Tube Patterning Cell Projection Organization Embryonic Camera-type Eye Development Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Intraciliary Anterograde Transport Post-anal Tail Morphogenesis Intraciliary Transport Embryonic Digit Morphogenesis Negative Regulation Of Smoothened Signaling Pathway Animal Organ Development System Development Negative Regulation Of Defense Response To Virus Defense Response To Virus Cilium Assembly Regulation Of Microtubule Cytoskeleton Organization
Pathways			Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Adiponectin levels ( 26299439) Alcohol consumption (max-drinks) ( 29460428) Alzheimer's disease ( 22430674) Aspartate aminotransferase levels ( 33339817) Basal cell carcinoma ( 33549134) Chronic obstructive pulmonary disease ( 32222710) Craniofacial microsomia ( 26853712) Daytime nap ( 33568662) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hematocrit ( 32888494) Hemoglobin ( 32888494) Knee osteoarthritis ( 27696742) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Obstetric antiphospholipid syndrome ( 28424481) Rapid automised naming of digits ( 30741946) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 28957414 27863252) RR interval (heart rate) ( 20031603) Takayasu arteritis ( 25604533) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429)	Chronotype ( 30696823) FEV1 ( 30804560) Intraocular pressure ( 29617998 29785010 30054594) Iris characteristics ( 21835309) Lung function (FEV1/FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Morning person ( 30696823) Refractive astigmatism ( 30306274) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		2 interacting genes: TRAF3IP1 YEATS4	31 interacting genes: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT ITSN1 MACF1 OLFM1 PCNT SFR1 SGF29 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 UBXN10 WAC
Entrez ID		55691	26146
HPRD ID		13553	09571
Ensembl ID		ENSG00000151474	ENSG00000204104
Uniprot IDs		Q9NW91 Q9P2Q2	Q8TDR0
PDB IDs			2EQO 8KCQ
Enriched GO Terms of Interacting Partners?		Histone H3K27ac Reader Activity Histone H3K18ac Reader Activity Post-anal Tail Morphogenesis Negative Regulation Of Interferon-beta Production Intraciliary Transport Particle B Embryonic Camera-type Eye Development Neural Tube Patterning Negative Regulation Of Defense Response To Virus Intraciliary Anterograde Transport Morphogenesis Of A Polarized Epithelium Embryonic Heart Tube Development NuA4 Histone Acetyltransferase Complex	Golgi To Plasma Membrane Transport Post-Golgi Vesicle-mediated Transport Positive Regulation Of Cellular Component Organization Vesicle-mediated Transport To The Plasma Membrane Regulation Of Postsynapse Organization Organelle Organization Regulation Of Neuron Projection Development Positive Regulation Of Axonogenesis Axo-dendritic Transport Regulation Of Axon Extension Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Regulation Of Cellular Component Organization Positive Regulation Of Cell Projection Organization Golgi To Plasma Membrane Protein Transport Cytoskeleton Organization Positive Regulation Of Axon Extension Meiotic Chromosome Condensation Establishment Of Protein Localization Condensin Complex Positive Regulation Of Chromosome Condensation Cilium Assembly Positive Regulation Of Cell Differentiation Regulation Of Axonogenesis Golgi Vesicle Transport Regulation Of Dendritic Spine Development Dendritic Spine Establishment Of Protein Localization To Plasma Membrane Vesicle-mediated Transport Cilium Organization CD40 Receptor Complex TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Synapse Organization Axon Cytoplasm Axonal Transport Cellular Localization Organelle Assembly Regulation Of Developmental Growth Transport Along Microtubule Clathrin-coated Pit MyD88-independent Toll-like Receptor Signaling Pathway Meiotic Chromosome Segregation Regulation Of Chromosome Condensation Endosome Molecular Adaptor Activity Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Developmental Process Plasma Membrane Bounded Cell Projection Assembly Signaling Adaptor Activity Mitotic Chromosome Condensation
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