MYH10 and S100A4

Number of citations of the paper that reports this interaction (PMID 9405067)
19

Data Source:
HPRD (in vitro)

		MYH10	S100A4
Gene Name		myosin, heavy chain 10, non-muscle	S100 calcium binding protein A4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Mitochondrion Spindle Plasma Membrane Cell Cortex Actin Cytoskeleton Myosin Complex Myosin II Complex Lamellipodium Axon Growth Cone Midbody Neuromuscular Junction Cleavage Furrow Actomyosin Neuronal Cell Body Dendritic Spine Extracellular Vesicular Exosome Myosin II Filament	Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Actin-dependent ATPase Activity ADP Binding Actin Filament Binding	Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Mitotic Cytokinesis In Utero Embryonic Development Neuron Migration Plasma Membrane Repair Exocytosis Substrate-dependent Cell Migration, Cell Extension Nuclear Migration Cell Adhesion Axon Guidance Adult Heart Development Cell Proliferation Regulation Of Cell Shape Fourth Ventricle Development Lateral Ventricle Development Third Ventricle Development Cerebellar Purkinje Cell Layer Development Actin Filament-based Movement Actomyosin Structure Organization Ephrin Receptor Signaling Pathway Neuromuscular Process Controlling Balance Cardiac Myofibril Assembly Ventricular Cardiac Muscle Cell Development Retina Development In Camera-type Eye	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		EPHA-mediated growth cone collapse Axon guidance Semaphorin interactions EPH-Ephrin signaling Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APC BCAP31 KIAA0368 MYH9 PBX1 S100A4 YWHAE YWHAG ZNF512B	22 interactors: ACTA1 ANXA2 BAG6 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 NOV PPFIBP1 S100A1 S100B S100P SEPT2 SEPT6 SEPT7 SMAD3 TP53 TPM2 TPM3 UNC119
Entrez ID		4628	6275
HPRD ID		01178	15914
Ensembl ID		ENSG00000133026	ENSG00000196154
Uniprot IDs		B2RWP9 G1UI33 P35580 Q9BWG0	P26447
PDB IDs			1M31 2LNK 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4ETO 4HSZ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Cell Death Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Stem Cell Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Proximal/distal Pattern Formation Generation Of Neurons Regulation Of Signal Transduction Neurogenesis Thymus Development Stem Cell Differentiation Positive Regulation Of Mitochondrion Organization Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Signaling Somatic Stem Cell Maintenance Apoptotic Process Programmed Cell Death Execution Phase Of Apoptosis Cell Cycle Process Positive Regulation Of Organelle Organization Cell Death Death Cell Differentiation Regulation Of Mitochondrion Organization Cytokinesis Nervous System Development Regulation Of Heart Rate By Hormone Negative Regulation Of Peptidyl-serine Dephosphorylation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process G2/M Transition Of Mitotic Cell Cycle Cell Cycle Negative Regulation Of Protein Serine/threonine Kinase Activity Protein Transport Hemopoiesis Regulation Of Apoptotic Process Establishment Of Protein Localization Stem Cell Maintenance Negative Regulation Of Odontogenesis System Development Regulation Of Proteolysis Mitotic Cell Cycle Process Regulation Of Cell Death Uropod Organization Establishment Of Meiotic Spindle Localization	Actin Filament-based Movement Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Cell Cycle Process Cytokinesis Cell Cycle Actin Filament-based Process Muscle Contraction Cell Division Movement Of Cell Or Subcellular Component Muscle System Process Regulation Of Cell Shape Plasma Membrane Repair Response To External Stimulus Anatomical Structure Morphogenesis Cellular Component Assembly Anatomical Structure Formation Involved In Morphogenesis Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Response To Abiotic Stimulus Mitotic Cell Cycle Regulation Of Cell Morphogenesis Cellular Response To Light Stimulus Cell Projection Morphogenesis Membrane Organization Cell Part Morphogenesis Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cell Development Response To Hypoxia Cellular Response To Oxygen Levels Actomyosin Structure Organization Signal Transduction By P53 Class Mediator Wound Healing Response To Light Stimulus Response To Stimulus Regulation Of Protein Stability Cellular Response To Radiation Cell Morphogenesis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To Wounding Cell Differentiation Anatomical Structure Development Immune System Process Cellular Response To Stimulus System Development Cell Projection Organization Positive Regulation Of Transport Cell Adhesion
Tagcloud ?		accordance aorta arteries atherosclerosis carotid ciclin d2 expresses functionality hemodynamic hyperplasia immunocitochemistry immunostaining intima labelling ligated ligation modulates morphometric neointimal reinforce remodelling restenosis sm22alpha stenotic thymidine transgenic tritiated vsmc	aldh1 anatomically area areas biomarkers cadherin cd44 central detailed egfr expressions fgfr1 heterogeneous immunohistochemical lymph metastatic molecules node nodes peripheral precise prediction recurrence relationships shorter sox2 squamous staining vegfr2
Tagcloud (Difference) ?		accordance aorta arteries atherosclerosis carotid ciclin d2 expresses functionality hemodynamic hyperplasia immunocitochemistry immunostaining intima labelling ligated ligation modulates morphometric neointimal reinforce remodelling restenosis sm22alpha stenotic thymidine transgenic tritiated vsmc	aldh1 anatomically area areas biomarkers cadherin cd44 central detailed egfr expressions fgfr1 heterogeneous immunohistochemical lymph metastatic molecules node nodes peripheral precise prediction recurrence relationships shorter sox2 squamous staining vegfr2
Tagcloud (Intersection) ?