ZNF436 and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF436	CCDC57
Description		zinc finger protein 436	coiled-coil domain containing 57
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Cytoplasm Centrosome Centriole Spindle Cytoskeleton Spindle Microtubule Centriolar Satellite
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		A body shape index ( 34021172) Estimated glomerular filtration rate ( 30604766 31015462) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Waist-hip index ( 34021172)	Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: CCDC125 CCDC57 CLK2 CREB1 KDM1A KIF9 NTAQ1 OGT PRMT5 PRMT6 SUV39H1 TRIM55 TRIM63 ZNF580	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 CATSPERT CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SAXO4 SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPMIP2 SPMIP6 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		80818	284001
HPRD ID		15793	14150
Ensembl ID		ENSG00000125945	ENSG00000176155
Uniprot IDs		A0AAA9YHR6 Q9C0F3	A0A590UJT6 Q2TAC2
PDB IDs
Enriched GO Terms of Interacting Partners?		Circadian Rhythm Histone Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Arginine N-methyltransferase Activity Histone H4R3 Methyltransferase Activity Protein Modification Process Regulation Of Transcription By Glucose Protein-arginine N-methyltransferase Activity Rhythmic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Small Molecule Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Transferase Activity Identical Protein Binding Histone Methyltransferase Complex Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Methyltransferase Activity Chromatin Organization Negative Regulation Of RNA Metabolic Process Methylation Negative Regulation Of Metabolic Process Regulation Of Gluconeogenesis Protein Metabolic Process Regulation Of Multicellular Organismal Process Chemotaxis To Arachidonate Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Glycolytic Process Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Protein-N-terminal Glutamine Amidohydrolase Activity Histone H2AR3 Methyltransferase Activity Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Multicellular Organism Growth Chromatin Remodeling Epigenetic Regulation Of Gene Expression Circadian Regulation Of Gene Expression Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Carbohydrate Catabolic Process P53 Binding Peptidyl-arginine N-methylation Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Protein-N-terminal Asparagine Amidohydrolase Activity Histone H3R2 Methyltransferase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of ATP Metabolic Process	Protein Binding Spliceosomal Complex Nucleus Cytoskeleton MRNA Splicing, Via Spliceosome RNA Splicing Axonemal A Tubule Inner Sheath RNA Splicing, Via Transesterification Reactions
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