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MED9 and CBX4
Number of citations of the paper that reports this interaction (PMID
14638676
)
7
Data Source:
HPRD
(in vitro)
MED9
CBX4
Gene Name
mediator complex subunit 9
chromobox homolog 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mediator Complex
Nucleus
Nucleoplasm
Nuclear Speck
PcG Protein Complex
PRC1 Complex
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
Chromatin Binding
Transcription Corepressor Activity
Single-stranded RNA Binding
Protein Binding
Ligase Activity
Enzyme Binding
SUMO Binding
Methylated Histone Binding
Transcription Regulatory Region DNA Binding
Phosphoprotein Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Chromatin Modification
Protein Sumoylation
Negative Regulation Of Apoptotic Process
Negative Regulation Of Transcription, DNA-templated
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Oxidative Stress Induced Senescence
Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions
26 interactors:
APP
CBX4
CDK8
MED1
MED11
MED12
MED13
MED14
MED16
MED18
MED19
MED22
MED23
MED24
MED25
MED26
MED27
MED28
MED29
MED30
MED31
MED4
MED6
MED7
MED8
USP47
18 interactors:
CBS
CSNK2B
CTBP1
CTBP2
FHL1
HIST3H3
KMT2A
LNX2
MBD1
MED9
RB1
RING1
RNF2
SATB1
SKIL
SUV39H1
UBE2I
ZEB2
Entrez ID
55090
8535
HPRD ID
14383
04357
Ensembl ID
ENSG00000141026
ENSG00000141582
Uniprot IDs
Q9NWA0
O00257
PDB IDs
2K28
3I8Z
Enriched GO Terms of Interacting Partners
?
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Androgen Receptor Signaling Pathway
Biosynthetic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of Metabolic Process
Intracellular Receptor Signaling Pathway
Stem Cell Maintenance
Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Stem Cell Development
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cellular Process
Positive Regulation Of Gene Expression
Stem Cell Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Cell Differentiation
Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Cell Differentiation
Cell Development
Positive Regulation Of Metabolic Process
Regulation Of Receptor Activity
Cellular Process
Developmental Growth Involved In Morphogenesis
Negative Regulation Of Fibroblast Proliferation
Axis Elongation
Positive Regulation Of Receptor Activity
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Thyroid Hormone Mediated Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Chromatin Modification
Histone Modification
RNA Metabolic Process
Chromosome Organization
Cellular Nitrogen Compound Metabolic Process
Chromatin Organization
Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Viral Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Transcription From RNA Polymerase II Promoter
Histone H2A Monoubiquitination
Anterior/posterior Pattern Specification
Histone H2A Ubiquitination
Cellular Metabolic Process
Regulation Of Metabolic Process
White Fat Cell Differentiation
Developmental Process
Histone Methylation
Histone Monoubiquitination
Negative Regulation Of Cell Proliferation
Viral Genome Replication
Organelle Organization
Peptidyl-lysine Trimethylation
Protein Methylation
Histone Ubiquitination
Cell Cycle
Cell Differentiation
Pattern Specification Process
Tagcloud
?
3p
accordingly
bodies
brachyury
cbx7
chemicals
ectodermal
embryoid
endodermal
fgf5
foxa2
ideal
markers
meanwhile
mebs
mesodermal
nanog
nestin
oct4
pcg
perfluorooctane
pfos
pluripotency
polycomb
poses
sma
sox17
sox2
sulfonate
Tagcloud (Difference)
?
3p
accordingly
bodies
brachyury
cbx7
chemicals
ectodermal
embryoid
endodermal
fgf5
foxa2
ideal
markers
meanwhile
mebs
mesodermal
nanog
nestin
oct4
pcg
perfluorooctane
pfos
pluripotency
polycomb
poses
sma
sox17
sox2
sulfonate
Tagcloud (Intersection)
?