MED9 and MED18

Number of citations of the paper that reports this interaction (PMID 15175163)
80

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		MED9	MED18
Gene Name		mediator complex subunit 9	mediator complex subunit 18
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mediator Complex	Mediator Complex
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Protein Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: APP CBX4 CDK8 MED1 MED11 MED12 MED13 MED14 MED16 MED18 MED19 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 USP47	8 interactors: CAMK2B HOMEZ MED20 MED31 MED9 THOC7 TRIM39 USP49
Entrez ID		55090	54797
HPRD ID		14383	17476
Ensembl ID		ENSG00000141026	ENSG00000130772
Uniprot IDs		Q9NWA0	B4DJL3 Q9BUE0
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Androgen Receptor Signaling Pathway Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Stem Cell Maintenance Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Stem Cell Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Gene Expression Stem Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cell Differentiation Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Differentiation Cell Development Positive Regulation Of Metabolic Process Regulation Of Receptor Activity Cellular Process Developmental Growth Involved In Morphogenesis Negative Regulation Of Fibroblast Proliferation Axis Elongation Positive Regulation Of Receptor Activity Regulation Of G2/M Transition Of Mitotic Cell Cycle Thyroid Hormone Mediated Signaling Pathway	RNA Metabolic Process Gene Expression Inhibitory G-protein Coupled Receptor Phosphorylation Histone H2B Conserved C-terminal Lysine Deubiquitination Activation Of Meiosis Involved In Egg Activation Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Heterocycle Metabolic Process Activation Of Meiosis Cellular Aromatic Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Synaptic Transmission, Cholinergic Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Viral MRNA Export From Host Cell Nucleus Nitrogen Compound Metabolic Process Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Skeletal Muscle Adaptation Regulation Of Synapse Structural Plasticity Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Dendritic Spine Morphogenesis RNA Splicing Positive Regulation Of Synapse Maturation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Meiotic Nuclear Division Histone Deubiquitination Egg Activation Regulation Of Synapse Maturation Regulation Of Protein Catabolic Process MRNA Processing Positive Regulation Of Dendritic Spine Development Intracellular Transport Of Virus Regulation Of Cellular Response To Heat Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Dendritic Spine Morphogenesis
Tagcloud ?			aba abscisic arabidopsis associates conveys cues deregulated engender evolutionarily flowering frigida4 glutaredoxins grx480 grxs13 h5 insensitive mediator multifunctional occupancy reinforcing termination terminator thioredoxin tri trx underpinning yang1 yin yy1
Tagcloud (Difference) ?			aba abscisic arabidopsis associates conveys cues deregulated engender evolutionarily flowering frigida4 glutaredoxins grx480 grxs13 h5 insensitive mediator multifunctional occupancy reinforcing termination terminator thioredoxin tri trx underpinning yang1 yin yy1
Tagcloud (Intersection) ?