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MED9 and MED14
Number of citations of the paper that reports this interaction (PMID
14638676
)
7
Data Source:
HPRD
(in vitro)
MED9
MED14
Gene Name
mediator complex subunit 9
mediator complex subunit 14
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Mediator Complex
Nucleus
Nucleoplasm
Membrane
Mediator Complex
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
RNA Polymerase II Transcription Cofactor Activity
Transcription Cofactor Activity
Transcription Coactivator Activity
Receptor Activity
Protein Binding
Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Vitamin D Receptor Binding
Thyroid Hormone Receptor Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Stem Cell Maintenance
Intracellular Steroid Hormone Receptor Signaling Pathway
Androgen Receptor Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
26 interactors:
APP
CBX4
CDK8
MED1
MED11
MED12
MED13
MED14
MED16
MED18
MED19
MED22
MED23
MED24
MED25
MED26
MED27
MED28
MED29
MED30
MED31
MED4
MED6
MED7
MED8
USP47
20 interactors:
ACTN1
ACTN2
AR
CTDP1
DCTN1
ESR1
ESR2
HNF4A
MED1
MED29
MED9
MYC
NECAB2
NR3C1
PARP1
PPARGC1A
SREBF1
STAT2
UACA
VDR
Entrez ID
55090
9282
HPRD ID
14383
02172
Ensembl ID
ENSG00000141026
ENSG00000180182
Uniprot IDs
Q9NWA0
O60244
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Androgen Receptor Signaling Pathway
Biosynthetic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of Metabolic Process
Intracellular Receptor Signaling Pathway
Stem Cell Maintenance
Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Stem Cell Development
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cellular Process
Positive Regulation Of Gene Expression
Stem Cell Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Cell Differentiation
Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Cell Differentiation
Cell Development
Positive Regulation Of Metabolic Process
Regulation Of Receptor Activity
Cellular Process
Developmental Growth Involved In Morphogenesis
Negative Regulation Of Fibroblast Proliferation
Axis Elongation
Positive Regulation Of Receptor Activity
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Thyroid Hormone Mediated Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Transcription From RNA Polymerase II Promoter
Intracellular Receptor Signaling Pathway
Transcription, DNA-templated
RNA Biosynthetic Process
Cellular Response To Hormone Stimulus
Hormone-mediated Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Cellular Response To Lipid
Intracellular Steroid Hormone Receptor Signaling Pathway
Cellular Response To Steroid Hormone Stimulus
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Steroid Hormone Mediated Signaling Pathway
RNA Metabolic Process
Regulation Of Metabolic Process
Response To Hormone
Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Cellular Macromolecule Biosynthetic Process
Response To Steroid Hormone
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Response To Organic Substance
Mammary Gland Branching Involved In Pregnancy
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Metabolic Process
Response To Lipid
Positive Regulation Of Cellular Biosynthetic Process
Response To Organic Cyclic Compound
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Transcription, DNA-templated
Nucleobase-containing Compound Metabolic Process
Regulation Of Signaling
Regulation Of Apoptotic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Cell Death
Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Gland Morphogenesis
Positive Regulation Of Metabolic Process
Mammary Gland Duct Morphogenesis
Regulation Of Signal Transduction
Regulation Of Transcription, DNA-templated
Tagcloud
?
bridges
cha1
eliminated
eukaryotes
gal11
kin28
machinery
med15
med17
med18
mediator
module
modules
paf1
rbp1
recruitment
remodeling
rgr1
ser2
ser5
severely
snf
srb4
srb5
swi
tata
tbp
ts
unaffected
Tagcloud (Difference)
?
bridges
cha1
eliminated
eukaryotes
gal11
kin28
machinery
med15
med17
med18
mediator
module
modules
paf1
rbp1
recruitment
remodeling
rgr1
ser2
ser5
severely
snf
srb4
srb5
swi
tata
tbp
ts
unaffected
Tagcloud (Intersection)
?