MED9 and MED14

Number of citations of the paper that reports this interaction (PubMedID 14638676)
0

Data Source:
HPRD (in vitro)

		MED9	MED14
Description		mediator complex subunit 9	mediator complex subunit 14
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex	Nucleus Nucleoplasm Membrane Mediator Complex Core Mediator Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Vitamin D Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Somatic Stem Cell Population Maintenance Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Birth weight ( 31043758) Estimated glomerular filtration rate ( 31152163) Fasting glucose ( 34059833) Two-hour glucose ( 34059833)	Migraine ( 27322543)
Interacting Genes		27 interacting genes: APP CBX4 CDK8 MED1 MED11 MED12 MED13 MED14 MED16 MED18 MED19 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 UBC USP47	20 interacting genes: ACTN1 ACTN2 AR CEBPA DCTN1 ESR1 ESR2 FBXL17 HNF4A MED1 MED29 MED9 NECAB2 NR3C1 PARP1 PPARGC1A SREBF1 STAT2 UACA VDR
Entrez ID		55090	9282
HPRD ID		14383	02172
Ensembl ID		ENSG00000141026	ENSG00000180182
Uniprot IDs		Q9NWA0	O60244
PDB IDs		7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8T9D 8TQW 8TRH	7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Mediator Complex Core Mediator Complex Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Protein-DNA Complex Assembly Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Vitamin D Receptor Binding Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Protein-containing Complex Organization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Coactivator Activity Nucleoplasm Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Thyroid Hormone Receptor Binding Positive Regulation Of Metabolic Process Ubiquitin Ligase Complex Somatic Stem Cell Population Maintenance Cellular Component Assembly Regulation Of Gene Expression Nucleus Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Stem Cell Population Maintenance Maintenance Of Cell Number Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Post-translational Protein Modification Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Protein Ubiquitination CKM Complex	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nuclear Receptor Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Intracellular Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of Biosynthetic Process Estrogen Response Element Binding Sequence-specific DNA Binding Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Mammary Gland Branching Involved In Pregnancy Nuclear Steroid Receptor Activity Hormone-mediated Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process DNA-templated Transcription DNA-binding Transcription Factor Activity Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Steroid Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Response To Lipid Nucleoplasm Response To Steroid Hormone Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Primary Metabolic Process Response To Hormone RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway DNA Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Chromatin Binding Transcription Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
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