MED9 and MED19

Number of citations of the paper that reports this interaction (PubMedID 14638676)
0

Data Source:
HPRD (in vitro)

		MED9	MED19
Description		mediator complex subunit 9	mediator complex subunit 19
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex	Nucleus Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Transcription Coregulator Activity Protein Binding	Transcription Coregulator Activity Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions
Drugs
Diseases
GWAS		Birth weight ( 31043758) Estimated glomerular filtration rate ( 31152163) Fasting glucose ( 34059833) Two-hour glucose ( 34059833)	Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Reticulocyte count ( 32888494) Schizophrenia ( 25056061 28991256 29483656)
Interacting Genes		27 interacting genes: APP CBX4 CDK8 MED1 MED11 MED12 MED13 MED14 MED16 MED18 MED19 MED22 MED23 MED24 MED25 MED26 MED27 MED28 MED29 MED30 MED31 MED4 MED6 MED7 MED8 UBC USP47	19 interacting genes: APP DCK DHRS7B DTX2 GRB2 HLCS KANK2 MED17 MED27 MED31 MED8 MED9 MSX1 NEDD9 NFKBIA OSTF1 RADIL RIPPLY1 ZNF76
Entrez ID		55090	219541
HPRD ID		14383	17477
Ensembl ID		ENSG00000141026	ENSG00000156603
Uniprot IDs		Q9NWA0	A0JLT2 J3KR33
PDB IDs		7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8T9D 8TQW 8TRH	7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Mediator Complex Core Mediator Complex Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Protein-DNA Complex Assembly Transcription Coregulator Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Vitamin D Receptor Binding Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Protein-containing Complex Organization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Coactivator Activity Nucleoplasm Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Thyroid Hormone Receptor Binding Positive Regulation Of Metabolic Process Ubiquitin Ligase Complex Somatic Stem Cell Population Maintenance Cellular Component Assembly Regulation Of Gene Expression Nucleus Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Stem Cell Population Maintenance Maintenance Of Cell Number Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Post-translational Protein Modification Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Protein Ubiquitination CKM Complex	Positive Regulation Of Transcription Initiation By RNA Polymerase II Core Mediator Complex Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Mediator Complex RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of DNA-templated Transcription Elongation Protein-DNA Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II Ubiquitin Ligase Complex Transcription Coregulator Activity Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Ubiquitin Protein Ligase Activity Positive Regulation Of RNA Metabolic Process Regulation Of Dendritic Spine Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Post-translational Protein Modification Notch Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Ephrin Receptor Binding Protein Ubiquitination Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Positive Regulation Of Macromolecule Biosynthetic Process Signal Transduction Involved In Regulation Of Gene Expression Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Biosynthetic Process Positive Regulation Of Lymphocyte Migration Nucleoplasm Guanyl-nucleotide Exchange Factor Adaptor Activity Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Negative Regulation Of Odontoblast Differentiation Acylglycerone-phosphate Reductase (NADP+) Activity Transcription Initiation At RNA Polymerase II Promoter Negative Regulation Of Protein Localization To Nucleus
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