GRPEL1 and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GRPEL1	CCDC57
Description		GrpE like 1, mitochondrial	coiled-coil domain containing 57
Image			No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor Nucleoplasm Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix	Cytoplasm Centrosome Centriole Spindle Cytoskeleton Spindle Microtubule Centriolar Satellite
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Unfolded Protein Binding Protein-folding Chaperone Binding	Protein Binding
	Biological Process	Protein Folding Intracellular Protein Transport Protein Import Into Mitochondrial Matrix	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494)	Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: CCDC57 ERCC6 GALT ISG15 POLR1C SPG21 WBP2	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 CATSPERT CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SAXO4 SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPMIP2 SPMIP6 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		80273	284001
HPRD ID		07550	14150
Ensembl ID		ENSG00000109519	ENSG00000176155
Uniprot IDs		Q9HAV7	A0A590UJT6 Q2TAC2
PDB IDs		9BLS 9BLT 9BLU
Enriched GO Terms of Interacting Partners?			Protein Binding Spliceosomal Complex Nucleus Cytoskeleton MRNA Splicing, Via Spliceosome RNA Splicing Axonemal A Tubule Inner Sheath RNA Splicing, Via Transesterification Reactions
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