PAAF1 and ANXA7

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		PAAF1	ANXA7
Description		proteasomal ATPase associated factor 1	annexin A7
Image		No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Vesicle Membrane Membrane Extracellular Matrix Chromaffin Granule Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Phosphatidylserine Binding RNA Binding Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding
	Biological Process		Autophagy Negative Regulation Of Gene Expression Epithelial Cell Differentiation Response To Calcium Ion Membrane Fusion Response To Phorbol 13-acetate 12-myristate
Pathways		Proteasome assembly Proteasome assembly
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196)	Copper levels ( 26025379)
Interacting Genes		6 interacting genes: ANXA7 PSMC1 PSMC4 PSMC6 TK1 UBLCP1	109 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5F1B ATP6V1A ATXN3 BAG6 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CREBBP CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 ERG28 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 HUNK INPP5K INTS11 KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OGT OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS1 RBBP4 RBM48 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		80227	310
HPRD ID		07761	01720
Ensembl ID		ENSG00000175575	ENSG00000138279
Uniprot IDs		F5H0C4 Q9BRP4	B2R657 P20073
PDB IDs			8W5S
Enriched GO Terms of Interacting Partners?		Proteasome-activating Activity Proteasome Regulatory Particle, Base Subcomplex Proteasome Accessory Complex Proteasome Complex Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Hydrolysis Activity Regulation Of Protein Catabolic Process Regulation Of Proteasome Assembly Proteasomal Protein Catabolic Process ATP Binding Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Modification-dependent Protein Catabolic Process Thymidine Kinase Activity Proteasome Regulatory Particle Binding Protein Catabolic Process DNA Synthesis Involved In Mitotic DNA Replication Proteolysis Involved In Protein Catabolic Process Nucleotide Binding Cytosolic Proteasome Complex Positive Regulation Of Inclusion Body Assembly Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Thymidine Biosynthetic Process Positive Regulation Of Protein Metabolic Process Catabolic Process Thymidine Metabolic Process Nucleus Chromaffin Granule Membrane Deoxyribonucleoside Monophosphate Biosynthetic Process Response To Phorbol 13-acetate 12-myristate Macromolecule Catabolic Process Proteasome Regulatory Particle Negative Regulation Of ATP-dependent Activity Pyrimidine Nucleoside Metabolic Process Proteolysis Inclusion Body Regulation Of Inclusion Body Assembly Regulation Of Protein-containing Complex Assembly Blastocyst Development Regulation Of Protein Metabolic Process Regulation Of ATP-dependent Activity Vesicle Membrane Pyrimidine-containing Compound Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process	TORC1 Signaling Extracellular Exosome TOR Signaling Negative Regulation Of TOR Signaling Negative Regulation Of TORC1 Signaling Regulation Of TORC1 Signaling Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of TOR Signaling Positive Regulation Of Metabolic Process Positive Regulation Of TORC1 Signaling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Cytoplasm Regulation Of Primary Metabolic Process Protein Modification By Small Protein Removal Extracellular Matrix Positive Regulation Of Biosynthetic Process Positive Regulation Of TOR Signaling Developmental Process Regulation Of Metabolic Process Macromolecule Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Perinuclear Region Of Cytoplasm Regulation Of Protein Metabolic Process Protein Deubiquitination Cellular Response To Nutrient Levels Regulation Of Proteolysis Histone H3T6 Kinase Activity Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Metabolic Process Platelet Alpha Granule Lumen Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Blood Microparticle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Protein Catabolic Process Cytoplasmic Translation Diacylglycerol-dependent Serine/threonine Kinase Activity Cytosol Nuclear Matrix Response To Interleukin-1 Response To Cytokine Regulation Of Protein Localization Negative Regulation Of Signal Transduction Calyx Of Held Negative Regulation Of Translational Initiation Protein Kinase C Signaling Proteasomal Protein Catabolic Process
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