PAAF1 and UBLCP1

Number of citations of the paper that reports this interaction (PubMedID 28539385)
62

Data Source:
BioGRID (pull down)

		PAAF1	UBLCP1
Description		proteasomal ATPase associated factor 1	ubiquitin like domain containing CTD phosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Cytosol	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Hydrolase Activity Metal Ion Binding Proteasome Regulatory Particle Binding
	Biological Process		Negative Regulation Of ATP-dependent Activity Regulation Of Proteasome Assembly
Pathways		Proteasome assembly Proteasome assembly
Drugs
Diseases
GWAS		Dimensional psychopathology (Cognitive) ( 29496196)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Inflammatory skin disease ( 25574825) Male-pattern baldness ( 29146897) Primary biliary cholangitis ( 26394269) Serum sulfate level ( 27412988) Tuberculosis susceptibility in HIV infection ( 26942285) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: ANXA7 PSMC1 PSMC4 PSMC6 TK1 UBLCP1	6 interacting genes: PAAF1 PSMC1 PSMC4 PSMC5 PSMD2 TSC22D4
Entrez ID		80227	134510
HPRD ID		07761	08318
Ensembl ID		ENSG00000175575	ENSG00000164332
Uniprot IDs		F5H0C4 Q9BRP4	Q8WVY7
PDB IDs			2KX3 2LGD 2M17
Enriched GO Terms of Interacting Partners?		Proteasome-activating Activity Proteasome Regulatory Particle, Base Subcomplex Proteasome Accessory Complex Proteasome Complex Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Hydrolysis Activity Regulation Of Protein Catabolic Process Regulation Of Proteasome Assembly Proteasomal Protein Catabolic Process ATP Binding Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Modification-dependent Protein Catabolic Process Thymidine Kinase Activity Proteasome Regulatory Particle Binding Protein Catabolic Process DNA Synthesis Involved In Mitotic DNA Replication Proteolysis Involved In Protein Catabolic Process Nucleotide Binding Cytosolic Proteasome Complex Positive Regulation Of Inclusion Body Assembly Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Thymidine Biosynthetic Process Positive Regulation Of Protein Metabolic Process Catabolic Process Thymidine Metabolic Process Nucleus Chromaffin Granule Membrane Deoxyribonucleoside Monophosphate Biosynthetic Process Response To Phorbol 13-acetate 12-myristate Macromolecule Catabolic Process Proteasome Regulatory Particle Negative Regulation Of ATP-dependent Activity Pyrimidine Nucleoside Metabolic Process Proteolysis Inclusion Body Regulation Of Inclusion Body Assembly Regulation Of Protein-containing Complex Assembly Blastocyst Development Regulation Of Protein Metabolic Process Regulation Of ATP-dependent Activity Vesicle Membrane Pyrimidine-containing Compound Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process	Proteasome Complex Proteasome Regulatory Particle, Base Subcomplex Proteasome Accessory Complex Proteasome-activating Activity Proteasome Regulatory Particle Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Macromolecule Catabolic Process ATP Hydrolysis Activity Regulation Of Proteolysis Proteolysis Positive Regulation Of Catabolic Process Nuclear Proteasome Complex Proteasome Storage Granule Regulation Of Protein Metabolic Process Thyrotropin-releasing Hormone Receptor Binding Cytosolic Proteasome Complex Positive Regulation Of Inclusion Body Assembly Positive Regulation Of Protein Metabolic Process Catabolic Process General Transcription Initiation Factor Binding Inclusion Body Transcription Factor Binding Regulation Of Inclusion Body Assembly ATP Binding Regulation Of Primary Metabolic Process TBP-class Protein Binding Protein Metabolic Process Enzyme Regulator Activity Blastocyst Development Cytosol Regulation Of Macromolecule Metabolic Process Nucleotide Binding
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