STX12 and DTX2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		STX12	DTX2
Gene Name		syntaxin 12	deltex 2, E3 ubiquitin ligase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endosome Membrane Endomembrane System Integral Component Of Membrane BLOC-1 Complex SNARE Complex Membrane Raft Phagocytic Vesicle Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Intracellular Protein Transport Vesicle Fusion Cholesterol Efflux Vesicle Docking Protein Stabilization	Notch Signaling Pathway Protein Ubiquitination
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: BLOC1S6 DTX2 EEA1 EPB42 HOMER1 NAPA NSG1 SNAP23 SNAP25 SNAP29 STX4	41 interactors: ABHD16A ALKBH4 ARNT2 C1orf94 DTX1 DTX3 EIF4ENIF1 FAM168A FHL2 GLYCTK GOLGA2 HDC HPCAL1 HPCAL4 KLC3 KRTAP26-1 MDC1 NCALD NCS1 NOTCH1 PLEKHF2 PLSCR1 QARS RBPMS RFX6 RHOXF2 RIMBP3 SEC22A SEC23B SPAG8 SPG21 STX12 SUMO1 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D3 UBE2D4 UBQLN4 VSNL1
Entrez ID		23673	113878
HPRD ID		06059	16841
Ensembl ID		ENSG00000117758	ENSG00000091073
Uniprot IDs		Q86Y82	Q86UW9
PDB IDs		2DNX
Enriched GO Terms of Interacting Partners?		Membrane Fusion Vesicle Organization Synaptic Vesicle Transport Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Fusion Synaptic Transmission Synaptic Vesicle Exocytosis Organelle Fusion Establishment Of Vesicle Localization Vesicle Localization Membrane Organization Cell-cell Signaling Neurotransmitter Secretion Establishment Of Organelle Localization Regulation Of Neurotransmitter Levels Synaptic Vesicle Priming Neurotransmitter Transport Organelle Localization Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Exocytosis Cellular Protein Complex Assembly Secretion By Cell Golgi Vesicle Transport Signaling Secretion Cellular Macromolecular Complex Assembly Synaptic Vesicle Docking Cell Communication Vesicle Docking Establishment Of Localization In Cell Membrane Docking Chemical Homeostasis Within A Tissue Cellular Localization Protein Complex Assembly Protein Localization Organelle Organization Vesicle Targeting Protein Transport Long-term Synaptic Potentiation Establishment Of Protein Localization Transport Regulation Of Synaptic Transmission Intracellular Transport Vesicle Docking Involved In Exocytosis Synaptic Vesicle To Endosome Fusion Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Positive Regulation Of Eosinophil Degranulation SNARE Complex Disassembly Cellular Component Assembly	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein K48-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transcription, DNA-templated RNA Biosynthetic Process Protein Modification By Small Protein Conjugation Transcription From RNA Polymerase II Promoter Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Innate Immune Response Protein K11-linked Ubiquitination RNA Metabolic Process Cellular Response To Oxygen Levels Heart Trabecula Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Hypoxia Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Notch Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Cellular Response To Stimulus Cellular Nitrogen Compound Metabolic Process Pancreatic Epsilon Cell Differentiation Glutaminyl-tRNA Aminoacylation Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Pancreatic D Cell Differentiation Cleavage Furrow Ingression Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Protein Polyubiquitination Glandular Epithelial Cell Differentiation Signal Transduction Trabecula Morphogenesis Positive Regulation Of Innate Immune Response Vesicle Fusion Regulation Of Immune System Process Prolyl-tRNA Aminoacylation Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Histamine Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?			algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Difference) ?			algae bioconversion diarrhetic dinophysistoxin dinophysistoxins distinctive distinguished dsp dtx1 dtxs eluted featured fragmentation imperative isomers mrm oa okadaic orbitrap poisoning polyether quick shellfish spectra toxins transitions unequivocal unless z
Tagcloud (Intersection) ?