MYO15B and ZBTB10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYO15B	ZBTB10
Description		myosin XVB	zinc finger and BTB domain containing 10
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GO Annotations	Cellular Component		Chromosome, Telomeric Region Nucleus Nucleoplasm
	Molecular Function		RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Telomeric DNA Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 29273806 31959851 31361310 30929738 32296059 27182965 34103634) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 22197932 26482879) Basal cell carcinoma ( 27539887 33549134) Body mass index ( 30271922 25673413 28892062) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hypothyroidism ( 22493691) Late-onset myasthenia gravis ( 26562150) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Self-reported allergy ( 23817569) Self-reported risk-taking behaviour ( 30271922) Sex hormone-binding globulin levels ( 22829776) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		96 interacting genes: ABI2 ADAMTSL4 BEND7 C7orf57 CARD9 CCNC CEP57L1 CFAP68 COIL CRX DNAJA3 DUSP21 ERAS FAM9B FHL2 GAB2 GADD45GIP1 GFAP GINS3 GPRASP3 HOXA1 IHO1 IKZF3 KATNBL1 KCNJ6 KIAA0408 KIF24 KIFC3 KLF4 KLHL12 KRT13 KRT31 KRT34 KRT35 KRT75 LIMS1 MTUS2 MYOZ3 NADSYN1 NBPF19 NDUFA12 NECAB2 NEDD4 NEFL NHSL2 NKAPD1 NOTCH2NLA NR1D2 NUP62 PAK5 PKNOX2 PLEKHA3 PNMA1 PNMA5 POU6F2 PPM1K PRKAR1B RAD54B RBM11 RCN1 RCN3 REL RPH3AL RUNDC3A SAXO4 SLA SORBS3 SPATC1L SPRED2 SSBP4 TCF12 TCF4 TEX13A TFIP11 TLE5 TPRN TRAF2 TRIM14 TRIM27 TRIM29 TRIM54 TSC22D4 UBQLN2 VGLL3 ZBED1 ZBTB10 ZBTB3 ZBTB32 ZBTB8A ZCCHC14 ZMAT1 ZNF114 ZNF438 ZNF774 ZNF837 ZNRD2	20 interacting genes: CDC7 CEP19 DCX DDX6 EHHADH FUT8 HRAS LSM4 MAGOHB MOB3C MORF4L1 MORF4L2 MYO15B PACRGL PHF1 RBM41 RNF8 USP20 UTP25 ZNF417
Entrez ID		80022	65986
HPRD ID			15689
Ensembl ID		ENSG00000266714	ENSG00000205189
Uniprot IDs		Q96JP2 Q9H614	Q96DT7 Q9H9H3
PDB IDs		2DLP	8GN3 8GN4
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Intermediate Filament Organization Protein Binding Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Intermediate Filament Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of RNA Metabolic Process Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Axonemal A Tubule Inner Sheath RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding	Positive Regulation Of Double-strand Break Repair Via Homologous Recombination P-body Assembly Positive Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Positive Regulation Of DNA Metabolic Process DNA Repair-dependent Chromatin Remodeling Regulation Of DNA Recombination Positive Regulation Of DNA Repair NuA4 Histone Acetyltransferase Complex Regulation Of Double-strand Break Repair Concave Side Of Sperm Head Nucleobase-containing Compound Metabolic Process Glycoprotein 6-alpha-L-fucosyltransferase Activity Alpha-(1->6)-fucosyltransferase Activity Fibroblast Proliferation Nucleic Acid Metabolic Process Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
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