MYO15B and NHSL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYO15B	NHSL2
Description		myosin XVB	NHS like 2
Image			No pdb structure
GO Annotations	Cellular Component
	Molecular Function		Protein Binding
	Biological Process		Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		96 interacting genes: ABI2 ADAMTSL4 BEND7 C7orf57 CARD9 CCNC CEP57L1 CFAP68 COIL CRX DNAJA3 DUSP21 ERAS FAM9B FHL2 GAB2 GADD45GIP1 GFAP GINS3 GPRASP3 HOXA1 IHO1 IKZF3 KATNBL1 KCNJ6 KIAA0408 KIF24 KIFC3 KLF4 KLHL12 KRT13 KRT31 KRT34 KRT35 KRT75 LIMS1 MTUS2 MYOZ3 NADSYN1 NBPF19 NDUFA12 NECAB2 NEDD4 NEFL NHSL2 NKAPD1 NOTCH2NLA NR1D2 NUP62 PAK5 PKNOX2 PLEKHA3 PNMA1 PNMA5 POU6F2 PPM1K PRKAR1B RAD54B RBM11 RCN1 RCN3 REL RPH3AL RUNDC3A SAXO4 SLA SORBS3 SPATC1L SPRED2 SSBP4 TCF12 TCF4 TEX13A TFIP11 TLE5 TPRN TRAF2 TRIM14 TRIM27 TRIM29 TRIM54 TSC22D4 UBQLN2 VGLL3 ZBED1 ZBTB10 ZBTB3 ZBTB32 ZBTB8A ZCCHC14 ZMAT1 ZNF114 ZNF438 ZNF774 ZNF837 ZNRD2	25 interacting genes: ABI3 ARID4B ATXN1 BTRC CLIC1 CTTN DYNLT1 GORASP2 HSF2BP INCA1 MAPK9 MTUS2 MYO15B NCK1 NCK2 PIH1D2 PLK1 PPP1R13B SH3RF1 SORBS3 TFCP2 TP53BP2 TRAF2 YWHAG YWHAH
Entrez ID		80022	340527
HPRD ID			15001
Ensembl ID		ENSG00000266714	ENSG00000204131
Uniprot IDs		Q96JP2 Q9H614	A0A0J9YY72 Q5HYW2
PDB IDs		2DLP
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Intermediate Filament Organization Protein Binding Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Intermediate Filament Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of RNA Metabolic Process Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Axonemal A Tubule Inner Sheath RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding	Cytoplasm Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Apoptotic Signaling Pathway Signaling Adaptor Activity Positive Regulation Of Protein Metabolic Process Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Vesicle Membrane Signal Transduction Lamellipodium Organization Positive Regulation Of Translation In Response To Stress Positive Regulation Of Actin Filament Polymerization Signal Complex Assembly Regulation Of Biological Quality Positive Regulation Of Supramolecular Fiber Organization Substrate-dependent Cell Migration, Cell Extension Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Translational Initiation In Response To Stress Receptor Tyrosine Kinase Binding Intracellular Signal Transduction TORC1 Signaling Positive Regulation Of Programmed Cell Death Modification Of Postsynaptic Actin Cytoskeleton Negative Regulation Of PERK-mediated Unfolded Protein Response Positive Regulation Of Cytoskeleton Organization Cytosol Regulation Of Protein Metabolic Process Positive Regulation Of Protein-containing Complex Assembly Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of PERK-mediated Unfolded Protein Response TOR Signaling Insulin-like Growth Factor Receptor Binding Positive Regulation Of Protein Polymerization Positive Regulation Of Signal Transduction Regulation Of Protein-containing Complex Assembly Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription By RNA Polymerase II Modification Of Postsynaptic Structure Modification Of Synaptic Structure Cytoskeletal Anchor Activity
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