ZBTB10

Description		zinc finger and BTB domain containing 10
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Telomeric DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 29273806 31959851 31361310 30929738 32296059 27182965 34103634) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 22197932 26482879) Basal cell carcinoma ( 27539887 33549134) Body mass index ( 30271922 25673413 28892062) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hypothyroidism ( 22493691) Late-onset myasthenia gravis ( 26562150) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Self-reported allergy ( 23817569) Self-reported risk-taking behaviour ( 30271922) Sex hormone-binding globulin levels ( 22829776) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		20 interacting genes: CDC7 CEP19 DCX DDX6 EHHADH FUT8 HRAS LSM4 MAGOHB MOB3C MORF4L1 MORF4L2 MYO15B PACRGL PHF1 RBM41 RNF8 USP20 UTP25 ZNF417
Entrez ID		65986
HPRD ID		15689
Ensembl ID		ENSG00000205189
Uniprot IDs		Q96DT7 Q9H9H3
PDB IDs		8GN3 8GN4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Double-strand Break Repair Via Homologous Recombination P-body Assembly Positive Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Positive Regulation Of DNA Metabolic Process DNA Repair-dependent Chromatin Remodeling Regulation Of DNA Recombination Positive Regulation Of DNA Repair NuA4 Histone Acetyltransferase Complex Regulation Of Double-strand Break Repair Concave Side Of Sperm Head Nucleobase-containing Compound Metabolic Process Glycoprotein 6-alpha-L-fucosyltransferase Activity Alpha-(1->6)-fucosyltransferase Activity Fibroblast Proliferation Nucleic Acid Metabolic Process Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
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