ZBTB10 and MOB3C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZBTB10	MOB3C
Description		zinc finger and BTB domain containing 10	MOB kinase activator 3C
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Telomeric DNA Binding Metal Ion Binding	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Signal Transduction
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 29273806 31959851 31361310 30929738 32296059 27182965 34103634) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 22197932 26482879) Basal cell carcinoma ( 27539887 33549134) Body mass index ( 30271922 25673413 28892062) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hypothyroidism ( 22493691) Late-onset myasthenia gravis ( 26562150) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Self-reported allergy ( 23817569) Self-reported risk-taking behaviour ( 30271922) Sex hormone-binding globulin levels ( 22829776) Urinary albumin-to-creatinine ratio ( 31511532)	Chronic kidney disease ( 30226566) Hypertension ( 30226566)
Interacting Genes		20 interacting genes: CDC7 CEP19 DCX DDX6 EHHADH FUT8 HRAS LSM4 MAGOHB MOB3C MORF4L1 MORF4L2 MYO15B PACRGL PHF1 RBM41 RNF8 USP20 UTP25 ZNF417	18 interacting genes: APP CMTM3 FAM118A FBXO7 IKZF4 KANK2 KRT40 LATS1 LATS2 NT5C2 PCYT1A PICK1 PTPN21 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10
Entrez ID		65986	148932
HPRD ID		15689	17584
Ensembl ID		ENSG00000205189	ENSG00000142961
Uniprot IDs		Q96DT7 Q9H9H3	Q70IA8 X6R3L3
PDB IDs		8GN3 8GN4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Double-strand Break Repair Via Homologous Recombination P-body Assembly Positive Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Positive Regulation Of DNA Metabolic Process DNA Repair-dependent Chromatin Remodeling Regulation Of DNA Recombination Positive Regulation Of DNA Repair NuA4 Histone Acetyltransferase Complex Regulation Of Double-strand Break Repair Concave Side Of Sperm Head Nucleobase-containing Compound Metabolic Process Glycoprotein 6-alpha-L-fucosyltransferase Activity Alpha-(1->6)-fucosyltransferase Activity Fibroblast Proliferation Nucleic Acid Metabolic Process Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Amide Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signaling Amyloid Fibril Formation Regulation Of Protein Localization To Nucleus Cytosol Positive Regulation Of Receptor Internalization Negative Regulation Of Cell Communication Identical Protein Binding Phosphate-containing Compound Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Hippo Signaling Negative Regulation Of Cell Cycle Negative Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of NLRP3 Inflammasome Complex Assembly Positive Regulation Of Hippo Signaling Amyloid-beta Complex Protein Homooligomerization Growth Cone Lamellipodium Neuron Projection Organization Negative Regulation Of Wnt Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Protein Modification Process L-tryptophan Catabolic Process To Acetyl-CoA Regulation Of Hippo Signaling Regulation Of Intracellular Estrogen Receptor Signaling Pathway Nucleoside Phosphotransferase Activity GMP Catabolic Process To Guanine Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of NLRP3 Inflammasome Complex Assembly Protein Metabolic Process Negative Regulation Of Protein Localization Positive Regulation Of Receptor-mediated Endocytosis Acetylcholine Receptor Activator Activity Positive Regulation Of Apoptotic Process Lipoprotein Particle Positive Regulation Of Protein Import Glial Cell Development
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