MYO15B and ERAS

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYO15B	ERAS
Description		myosin XVB	ES cell expressed Ras
Image			No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Membrane
	Molecular Function		Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding
	Biological Process		Signal Transduction Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS
Interacting Genes		96 interacting genes: ABI2 ADAMTSL4 BEND7 C7orf57 CARD9 CCNC CEP57L1 CFAP68 COIL CRX DNAJA3 DUSP21 ERAS FAM9B FHL2 GAB2 GADD45GIP1 GFAP GINS3 GPRASP3 HOXA1 IHO1 IKZF3 KATNBL1 KCNJ6 KIAA0408 KIF24 KIFC3 KLF4 KLHL12 KRT13 KRT31 KRT34 KRT35 KRT75 LIMS1 MTUS2 MYOZ3 NADSYN1 NBPF19 NDUFA12 NECAB2 NEDD4 NEFL NHSL2 NKAPD1 NOTCH2NLA NR1D2 NUP62 PAK5 PKNOX2 PLEKHA3 PNMA1 PNMA5 POU6F2 PPM1K PRKAR1B RAD54B RBM11 RCN1 RCN3 REL RPH3AL RUNDC3A SAXO4 SLA SORBS3 SPATC1L SPRED2 SSBP4 TCF12 TCF4 TEX13A TFIP11 TLE5 TPRN TRAF2 TRIM14 TRIM27 TRIM29 TRIM54 TSC22D4 UBQLN2 VGLL3 ZBED1 ZBTB10 ZBTB3 ZBTB32 ZBTB8A ZCCHC14 ZMAT1 ZNF114 ZNF438 ZNF774 ZNF837 ZNRD2	4 interacting genes: MYO15B PIK3CD PIK3R1 TLX3
Entrez ID		80022	3266
HPRD ID			02339
Ensembl ID		ENSG00000266714	ENSG00000187682
Uniprot IDs		Q96JP2 Q9H614	Q7Z444
PDB IDs		2DLP
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Intermediate Filament Organization Protein Binding Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Intermediate Filament Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of RNA Metabolic Process Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Axonemal A Tubule Inner Sheath RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding	Phosphatidylinositol 3-kinase Complex Phosphatidylinositol 3-kinase Complex, Class IA Phosphatidylinositol Phosphate Biosynthetic Process B Cell Differentiation Glycerophospholipid Biosynthetic Process Natural Killer Cell Chemotaxis Phosphatidylinositol Metabolic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Mast Cell Differentiation Regulation Of Neutrophil Apoptotic Process Positive Regulation Of Neutrophil Apoptotic Process Myeloid Leukocyte Migration Phospholipid Biosynthetic Process Leukocyte Migration Glycerophospholipid Metabolic Process Leukocyte Mediated Immunity Cell Migration Mast Cell Chemotaxis B Cell Activation T Cell Differentiation Phosphatidylinositol Biosynthetic Process Lymphocyte Differentiation Cell Motility B Cell Chemotaxis Myeloid Cell Differentiation Neutrophil Extravasation Myeloid Leukocyte Differentiation Kinase Regulator Activity Insulin Binding Perinuclear Endoplasmic Reticulum Membrane 1-phosphatidylinositol-3-kinase Regulator Activity Neurotrophin TRKA Receptor Binding Phosphatidylinositol 3-kinase Regulator Activity ErbB-3 Class Receptor Binding 1-phosphatidylinositol-4-phosphate 3-kinase Activity Mast Cell Migration 1-phosphatidylinositol-4,5-bisphosphate 3-kinase Activity Phosphatidylinositol 3-kinase Activator Activity Positive Regulation Of Myeloid Cell Apoptotic Process Respiratory Burst Involved In Defense Response Mononuclear Cell Differentiation Glycerolipid Metabolic Process Positive Regulation Of Epithelial Tube Formation T Cell Activation Positive Regulation Of Focal Adhesion Disassembly Phosphatidylinositol 3-kinase Regulatory Subunit Binding Phospholipid Metabolic Process 1-phosphatidylinositol-3-kinase Activity T Follicular Helper Cell Differentiation Leukocyte Differentiation
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