ZBTB10 and PACRGL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB10	PACRGL
Description		zinc finger and BTB domain containing 10	parkin coregulated like
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Telomeric DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 29273806 31959851 31361310 30929738 32296059 27182965 34103634) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 22197932 26482879) Basal cell carcinoma ( 27539887 33549134) Body mass index ( 30271922 25673413 28892062) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hypothyroidism ( 22493691) Late-onset myasthenia gravis ( 26562150) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Self-reported allergy ( 23817569) Self-reported risk-taking behaviour ( 30271922) Sex hormone-binding globulin levels ( 22829776) Urinary albumin-to-creatinine ratio ( 31511532)	Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		20 interacting genes: CDC7 CEP19 DCX DDX6 EHHADH FUT8 HRAS LSM4 MAGOHB MOB3C MORF4L1 MORF4L2 MYO15B PACRGL PHF1 RBM41 RNF8 USP20 UTP25 ZNF417	14 interacting genes: ALX1 BEX5 FAM3A GOLGA2 GRB2 MYF5 MYOG PIK3R3 RCN3 TASOR2 TRIM55 TRIM63 TXNRD3 ZBTB10
Entrez ID		65986	133015
HPRD ID		15689	14537
Ensembl ID		ENSG00000205189	ENSG00000163138
Uniprot IDs		Q96DT7 Q9H9H3	A8K679 D6RGK2 Q8N7B6
PDB IDs		8GN3 8GN4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Double-strand Break Repair Via Homologous Recombination P-body Assembly Positive Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Positive Regulation Of DNA Metabolic Process DNA Repair-dependent Chromatin Remodeling Regulation Of DNA Recombination Positive Regulation Of DNA Repair NuA4 Histone Acetyltransferase Complex Regulation Of Double-strand Break Repair Concave Side Of Sperm Head Nucleobase-containing Compound Metabolic Process Glycoprotein 6-alpha-L-fucosyltransferase Activity Alpha-(1->6)-fucosyltransferase Activity Fibroblast Proliferation Nucleic Acid Metabolic Process Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Skeletal Muscle Fiber Development Muscle Atrophy Striated Muscle Atrophy Regulation Of Skeletal Muscle Fiber Development Muscle Cell Fate Commitment Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Skeletal Muscle Tissue Development Regulation Of Skeletal Muscle Tissue Development Response To Electrical Stimulus Phosphotyrosine Residue Binding Regulation Of Striated Muscle Tissue Development Regulation Of Myotube Differentiation Regulation Of Muscle Organ Development Positive Regulation Of Myoblast Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Guanyl-nucleotide Exchange Factor Adaptor Activity E-box Binding Skeletal Muscle Cell Differentiation Skeletal Muscle Tissue Development Grb2-EGFR Complex Regulation Of Myoblast Differentiation Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Muscle Atrophy Negative Regulation Of Antifungal Innate Immune Response Immune Response Insulin Receptor Signaling Pathway Embryonic Skeletal System Morphogenesis Microtubule Regulation Of Striated Muscle Cell Differentiation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Defense Response To Symbiont Defense Response To Other Organism Negative Regulation Of Innate Immune Response RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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