RMI1 and PFDN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RMI1	PFDN1
Gene Name		RecQ mediated genome instability 1	prefoldin subunit 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Prefoldin Complex
	Molecular Function	Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding
	Biological Process	Reduction Of Food Intake In Response To Dietary Excess DNA Replication Response To Glucose Multicellular Organism Growth Glucose Homeostasis	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways			Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS		Response to statin therapy ( 20339536)
Protein-Protein Interactions		4 interactors: HSPA13 NR1H2 PFDN1 UBE3A	54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235
Entrez ID		80010	5201
HPRD ID		09867	05357
Ensembl ID		ENSG00000178966	ENSG00000113068
Uniprot IDs		Q9H9A7	O60925
PDB IDs		3MXN 3NBH 3NBI 4DAY
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of High-density Lipoprotein Particle Assembly Sperm Entry Intracellular Receptor Signaling Pathway Regulation Of High-density Lipoprotein Particle Assembly Negative Regulation Of Pinocytosis Negative Regulation Of Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Cholesterol Storage Positive Regulation Of Digestive System Process Positive Regulation Of Lipoprotein Lipase Activity Positive Regulation Of Fatty Acid Biosynthetic Process Regulation Of Cholesterol Homeostasis Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Cholesterol Efflux Negative Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Cholesterol Transport Regulation Of Proteolysis Negative Regulation Of Lipid Storage Regulation Of Triglyceride Biosynthetic Process Regulation Of Cholesterol Efflux Prostate Gland Growth Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Negative Regulation Of Lipid Transport Retinoic Acid Receptor Signaling Pathway Brain Development Head Development Positive Regulation Of Lipid Storage Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of Triglyceride Metabolic Process Regulation Of Cholesterol Transport Protein K48-linked Ubiquitination Negative Regulation Of Innate Immune Response Negative Regulation Of Cytokine-mediated Signaling Pathway Central Nervous System Development Androgen Receptor Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Protein Autoubiquitination Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Endocytosis Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Lipid Storage Positive Regulation Of Lipid Transport 'de Novo' Posttranslational Protein Folding	Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis
Tagcloud ?		annealing blm break catalyze cooperate debate dna2 endonuclease ends epistatically exonuclease helicase joining microhomology mre11 prerequisite rad50 recq resection rmi2 rpa sae2 sgs1 strand substitute topoiiialpha tracts wrn xrs2
Tagcloud (Difference) ?		annealing blm break catalyze cooperate debate dna2 endonuclease ends epistatically exonuclease helicase joining microhomology mre11 prerequisite rad50 recq resection rmi2 rpa sae2 sgs1 strand substitute topoiiialpha tracts wrn xrs2
Tagcloud (Intersection) ?