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RMI1 and NR1H2
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
RMI1
NR1H2
Gene Name
RecQ mediated genome instability 1
nuclear receptor subfamily 1, group H, member 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Protein Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Sequence-specific Transcription Regulatory Region DNA Binding RNA Polymerase II Transcription Factor Recruiting Transcription Factor Activity
DNA Binding
Steroid Hormone Receptor Activity
Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Apolipoprotein A-I Receptor Binding
Retinoid X Receptor Binding
ATPase Binding
Biological Process
Reduction Of Food Intake In Response To Dietary Excess
DNA Replication
Response To Glucose
Multicellular Organism Growth
Glucose Homeostasis
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Triglyceride Biosynthetic Process
Positive Regulation Of Cholesterol Efflux
Positive Regulation Of Lipid Storage
Negative Regulation Of Cholesterol Storage
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Lipid Transport
Positive Regulation Of Cholesterol Transport
Cholesterol Homeostasis
Steroid Hormone Mediated Signaling Pathway
Cellular Lipid Metabolic Process
Positive Regulation Of Fatty Acid Biosynthetic Process
Negative Regulation Of Proteolysis
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Retinoic Acid Receptor Signaling Pathway
Negative Regulation Of Pinocytosis
Positive Regulation Of Lipoprotein Lipase Activity
Negative Regulation Of Interferon-gamma-mediated Signaling Pathway
Positive Regulation Of High-density Lipoprotein Particle Assembly
Positive Regulation Of Pancreatic Juice Secretion
Positive Regulation Of Secretion Of Lysosomal Enzymes
Regulation Of Cholesterol Homeostasis
Pathways
Generic Transcription Pathway
Nuclear Receptor transcription pathway
Drugs
(3-{3-[[2-Chloro-3-(Trifluoromethyl)Benzyl](2,2-Diphenylethyl)Amino]Propoxy}Phenyl)Acetic Acid
Benzenesulfonyl
N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE
1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL
Diseases
GWAS
Response to statin therapy (
20339536
)
Protein-Protein Interactions
4 interactors:
HSPA13
NR1H2
PFDN1
UBE3A
46 interactors:
BAG6
C14orf1
CDKN1A
CHD3
COL4A5
CSAD
DUSP12
FAF1
FOXO3
HDAC4
HMGXB4
ING3
KDM1A
LAMC3
MDFI
MED1
MPP1
NCOA3
NCOA6
NCOR1
NCOR2
NPY
NR0B2
NRIP1
PCDH17
PRKCA
RARA
RMI1
ROBO2
RXRA
RXRB
RXRG
SCG5
SIRT1
SMPD1
SORBS2
SPRY2
SRC
SUV39H1
TMEM161A
UBE2D1
UBE2I
VDR
VIM
YY1
ZXDC
Entrez ID
80010
7376
HPRD ID
09867
02660
Ensembl ID
ENSG00000178966
ENSG00000131408
Uniprot IDs
Q9H9A7
B4DNM6
F1D8P7
M0R2F9
P55055
PDB IDs
3MXN
3NBH
3NBI
4DAY
1P8D
1PQ6
1PQ9
1PQC
1UPV
1UPW
3KFC
3L0E
4DK7
4DK8
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Secretion Of Lysosomal Enzymes
Positive Regulation Of Pancreatic Juice Secretion
Positive Regulation Of High-density Lipoprotein Particle Assembly
Sperm Entry
Intracellular Receptor Signaling Pathway
Regulation Of High-density Lipoprotein Particle Assembly
Negative Regulation Of Pinocytosis
Negative Regulation Of Interferon-gamma-mediated Signaling Pathway
Negative Regulation Of Cholesterol Storage
Positive Regulation Of Digestive System Process
Positive Regulation Of Lipoprotein Lipase Activity
Positive Regulation Of Fatty Acid Biosynthetic Process
Regulation Of Cholesterol Homeostasis
Positive Regulation Of Triglyceride Biosynthetic Process
Positive Regulation Of Cholesterol Efflux
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Positive Regulation Of Cholesterol Transport
Regulation Of Proteolysis
Negative Regulation Of Lipid Storage
Regulation Of Triglyceride Biosynthetic Process
Regulation Of Cholesterol Efflux
Prostate Gland Growth
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Response To Interferon-gamma
Negative Regulation Of Lipid Transport
Retinoic Acid Receptor Signaling Pathway
Brain Development
Head Development
Positive Regulation Of Lipid Storage
Positive Regulation Of Fatty Acid Metabolic Process
Regulation Of Fatty Acid Biosynthetic Process
Regulation Of Triglyceride Metabolic Process
Regulation Of Cholesterol Transport
Protein K48-linked Ubiquitination
Negative Regulation Of Innate Immune Response
Negative Regulation Of Cytokine-mediated Signaling Pathway
Central Nervous System Development
Androgen Receptor Signaling Pathway
Negative Regulation Of Response To Cytokine Stimulus
Protein Autoubiquitination
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Macrophage Derived Foam Cell Differentiation
Negative Regulation Of Endocytosis
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Lipid Storage
Positive Regulation Of Lipid Transport
'de Novo' Posttranslational Protein Folding
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Organ Development
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
DNA-templated Transcription, Initiation
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Response To Organic Substance
Intracellular Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Reproductive Structure Development
Reproductive System Development
System Development
Positive Regulation Of Gene Expression
Transcription, DNA-templated
Regulation Of Gene Expression
RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Response To Hormone
Multicellular Organismal Development
Cell Differentiation
Single Organism Reproductive Process
Anatomical Structure Development
Developmental Process Involved In Reproduction
Developmental Process
Reproductive Process
Cellular Response To Steroid Hormone Stimulus
Signal Transduction
Multicellular Organismal Reproductive Process
Multicellular Organism Reproduction
Cellular Response To Organic Substance
Cellular Response To Stimulus
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Regulation Of Nucleic Acid-templated Transcription
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of RNA Biosynthetic Process
Chromatin Organization
Response To Stimulus
Hormone-mediated Signaling Pathway
Regulation Of RNA Metabolic Process
Gene Expression
Positive Regulation Of Transcription, DNA-templated
Signaling
Tagcloud
?
annealing
blm
break
catalyze
cooperate
debate
dna2
endonuclease
ends
epistatically
exonuclease
helicase
joining
microhomology
mre11
prerequisite
rad50
recq
resection
rmi2
rpa
sae2
sgs1
strand
substitute
topoiiialpha
tracts
wrn
xrs2
Tagcloud (Difference)
?
annealing
blm
break
catalyze
cooperate
debate
dna2
endonuclease
ends
epistatically
exonuclease
helicase
joining
microhomology
mre11
prerequisite
rad50
recq
resection
rmi2
rpa
sae2
sgs1
strand
substitute
topoiiialpha
tracts
wrn
xrs2
Tagcloud (Intersection)
?