FAM57A and SLC3A2

Number of citations of the paper that reports this interaction (PMID 12270127)
1

Data Source:
HPRD (two hybrid, in vivo)

		FAM57A	SLC3A2
Gene Name		family with sequence similarity 57, member A	solute carrier family 3 (amino acid transporter heavy chain), member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Apical Plasma Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function		Double-stranded RNA Binding Catalytic Activity Calcium:sodium Antiporter Activity Protein Binding Neutral Amino Acid Transmembrane Transporter Activity Cation Binding Poly(A) RNA Binding
	Biological Process		Carbohydrate Metabolic Process Ion Transport Calcium Ion Transport Amino Acid Transport Blood Coagulation Tryptophan Transport Cell Growth Sodium Ion Transmembrane Transport Response To Exogenous DsRNA Leukocyte Migration Transmembrane Transport Leucine Import
Pathways			Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		2 interactors: GGT7 SLC3A2	11 interactors: EGFR FAM57A HNRNPD ICAM1 ITGB1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 VHL
Entrez ID		79850	6520
HPRD ID		13096	01148
Ensembl ID		ENSG00000167695	ENSG00000168003
Uniprot IDs		Q8TBR7	J3KPF3 P08195
PDB IDs			2DH2 2DH3
Enriched GO Terms of Interacting Partners?		Leucine Import Tryptophan Transport Aromatic Amino Acid Transport Leucine Transport Branched-chain Amino Acid Transport Amino Acid Import Leukotriene Biosynthetic Process Glutathione Biosynthetic Process Peptide Biosynthetic Process Leukotriene Metabolic Process Neutral Amino Acid Transport Icosanoid Biosynthetic Process Response To Exogenous DsRNA Unsaturated Fatty Acid Biosynthetic Process Glutathione Metabolic Process Response To DsRNA Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Amino Acid Transmembrane Transport Fatty Acid Biosynthetic Process Cell Growth Peptide Metabolic Process Amino Acid Transport	Leukocyte Migration Cell Migration Cell Motility Amino Acid Transmembrane Transport Amino Acid Transport Locomotion Neutral Amino Acid Transport Blood Coagulation Hemostasis L-alpha-amino Acid Transmembrane Transport Movement Of Cell Or Subcellular Component Regulation Of Body Fluid Levels Wound Healing Carboxylic Acid Transport Organic Acid Transport Response To Wounding Immune System Process Response To Stress Anion Transmembrane Transport Organic Anion Transport Anion Transport Cell Adhesion Mediated By Integrin Single Organismal Cell-cell Adhesion Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Vasoconstriction Ion Transmembrane Transport Response To Gonadotropin Cell Activation Viral Entry Into Host Cell Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Entry Into Host Cell Rhythmic Process Regulation Of Vasoconstriction Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Cell Migration Chemical Homeostasis Positive Regulation Of Cell Motility Response To Organic Cyclic Compound Positive Regulation Of Cellular Component Movement Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Mechanical Stimulus Positive Regulation Of Locomotion Negative Regulation Of Apoptotic Process Transmembrane Transport Negative Regulation Of Programmed Cell Death Ion Transport Alkanesulfonate Metabolic Process Response To Sulfur Dioxide D-alanine Transport
Tagcloud ?			adenocarcinoma anchorage approved braf cd74 consisting constitutively driver druggable erbb4 exclusively ezr fusion fusions her3 ima imas kiaa1468 kras mucinous mutually nih3t3 nrg1 oncogenic ret sequencing transcriptome trim24 tumorigenicity
Tagcloud (Difference) ?			adenocarcinoma anchorage approved braf cd74 consisting constitutively driver druggable erbb4 exclusively ezr fusion fusions her3 ima imas kiaa1468 kras mucinous mutually nih3t3 nrg1 oncogenic ret sequencing transcriptome trim24 tumorigenicity
Tagcloud (Intersection) ?