TLCD3A and SLC3A2

Number of citations of the paper that reports this interaction (PubMedID 12270127)
0

Data Source:
HPRD (two hybrid, in vivo)

		TLCD3A	SLC3A2
Description		TLC domain containing 3A	solute carrier family 3 member 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane	Nucleoplasm Lysosome Lysosomal Membrane Plasma Membrane Basal Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Apical Plasma Membrane Melanosome Neuronal Cell Body Apical Pole Of Neuron Synapse Extracellular Exosome Anchoring Junction Amino Acid Transport Complex
	Molecular Function	Protein Binding	Virus Receptor Activity RNA Binding Double-stranded RNA Binding Protein Binding Aromatic Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Exogenous Protein Binding
	Biological Process	Lipid Homeostasis	Carbohydrate Metabolic Process Calcium Ion Transport Amino Acid Transport Isoleucine Transport L-leucine Transport Methionine Transport Phenylalanine Transport Proline Transport Tryptophan Transport Tyrosine Transport Valine Transport Response To Exogenous DsRNA Symbiont Entry Into Host Cell Thyroid Hormone Transport L-histidine Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane
Pathways			Basigin interactions Amino acid transport across the plasma membrane Defective SLC7A7 causes lysinuric protein intolerance (LPI) Tryptophan catabolism
Drugs
Diseases
GWAS		joint destruction in rheumatoid arthritis (rapid vs slow) ( 33585033)	Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		2 interacting genes: GGT7 SLC3A2	18 interacting genes: CCR4 CEBPA EBP EGFR GPR37 HNRNPD ICAM1 ITGB1 KLHL20 MTNR1B NPSR1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 TLCD3A VHL
Entrez ID		79850	6520
HPRD ID		13096	01148
Ensembl ID		ENSG00000167695	ENSG00000168003
Uniprot IDs		I3L336 Q8TBR7	P08195
PDB IDs			2DH2 2DH3 6IRS 6IRT 6JMQ 6JMR 6S8V 7B00 7CCS 7CMH 7CMI 7DF1 7DSK 7DSL 7DSN 7DSQ 7EPZ 7P9U 7P9V 8A6L 8G0M 8IDA 8J8L 8J8M 8KDD 8KDF 8KDG 8KDH 8KDI 8KDJ 8KDN 8KDO 8KDP 8QEY 8WNS 8WNT 8WNY 8X0W 8XPU 8YLP
Enriched GO Terms of Interacting Partners?		Leukotriene C4 Gamma-glutamyl Transferase Activity Apical Pole Of Neuron Isoleucine Transport L-histidine Transport Exogenous Protein Binding Methionine Transport L-leucine Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane Phenylalanine Transport Amino Acid Transport Complex L-alanine Transmembrane Transport Aromatic Amino Acid Transmembrane Transporter Activity Valine Transport Tryptophan Transport L-alanine Import Across Plasma Membrane Tyrosine Transport L-alanine Transmembrane Transporter Activity Leukotriene D4 Biosynthetic Process Glutathione Hydrolase Activity Negative Regulation Of Response To Oxidative Stress Glutathione Catabolic Process L-alanine Transport Aromatic Amino Acid Transport Branched-chain Amino Acid Transport L-leucine Transport Proline Transport Thyroid Hormone Transport Glutathione Biosynthetic Process Alanine Transport Sulfur Amino Acid Transport Leukotriene Biosynthetic Process Neutral L-amino Acid Transmembrane Transporter Activity Basic Amino Acid Transport Peptide Biosynthetic Process Regulation Of Response To Oxidative Stress Leukotriene Metabolic Process Modified Amino Acid Catabolic Process Amino Acid Import Across Plasma Membrane Response To Exogenous DsRNA Icosanoid Biosynthetic Process Neutral Amino Acid Transport Response To DsRNA Fatty Acid Derivative Biosynthetic Process Glutathione Metabolic Process Peptide Metabolic Process L-alpha-amino Acid Transmembrane Transport Basal Plasma Membrane L-amino Acid Transport Double-stranded RNA Binding Fatty Acid Derivative Metabolic Process	L-amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transport L-alpha-amino Acid Transmembrane Transport L-amino Acid Transport Amino Acid Transmembrane Transport Negative Regulation Of Programmed Cell Death Amino Acid Transport Branched-chain Amino Acid Transport L-leucine Transport Organic Acid Transmembrane Transport Carboxylic Acid Transmembrane Transport Alanine Transport Neutral L-amino Acid Transmembrane Transporter Activity Transmembrane Transporter Activity Negative Regulation Of Apoptotic Process Organic Cation Transport L-leucine Import Across Plasma Membrane Microvillus Membrane Liver Development Response To Amino Acid Regulation Of Apoptotic Process Amino Acid Import Across Plasma Membrane Carboxylic Acid Transport Organic Acid Transport Valine Transport Regulation Of Programmed Cell Death L-leucine Transmembrane Transporter Activity Tryptophan Transport Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Organic Anion Transport Negative Regulation Of Catabolic Process Basal Plasma Membrane Aromatic Amino Acid Transport Thyroid Hormone Transport Organic Cation Transmembrane Transporter Activity Animal Organ Development Glycine Transport Negative Regulation Of Vasoconstriction Cellular Response To Amino Acid Stimulus Virus Receptor Activity Sulfur Amino Acid Transport Basolateral Plasma Membrane Vascular Process In Circulatory System Neuropeptide Signaling Pathway Learning Or Memory Gland Development Neuropeptide Receptor Activity Basic Amino Acid Transport Response To Cytokine
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