FAM57A and GGT7

Number of citations of the paper that reports this interaction (PMID 12270127)
1

Data Source:
HPRD (in vivo, two hybrid)

		FAM57A	GGT7
Gene Name		family with sequence similarity 57, member A	gamma-glutamyltransferase 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Integral Component Of Membrane Anchored Component Of External Side Of Plasma Membrane
	Molecular Function		Gamma-glutamyltransferase Activity Glutathione Hydrolase Activity
	Biological Process		Proteolysis Glutathione Metabolic Process Glutathione Biosynthetic Process Leukotriene Biosynthetic Process
Pathways			Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Aflatoxin activation and detoxification Glutathione synthesis and recycling Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Glutathione conjugation Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective ACY1 causes encephalopathy Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		2 interactors: GGT7 SLC3A2	5 interactors: FAM57A GPR25 LHFPL5 MALL TMEM242
Entrez ID		79850	2686
HPRD ID		13096	07488
Ensembl ID		ENSG00000167695	ENSG00000131067
Uniprot IDs		Q8TBR7	A0PJJ9 Q9UJ14
PDB IDs
Enriched GO Terms of Interacting Partners?		Leucine Import Tryptophan Transport Aromatic Amino Acid Transport Leucine Transport Branched-chain Amino Acid Transport Amino Acid Import Leukotriene Biosynthetic Process Glutathione Biosynthetic Process Peptide Biosynthetic Process Leukotriene Metabolic Process Neutral Amino Acid Transport Icosanoid Biosynthetic Process Response To Exogenous DsRNA Unsaturated Fatty Acid Biosynthetic Process Glutathione Metabolic Process Response To DsRNA Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Amino Acid Transmembrane Transport Fatty Acid Biosynthetic Process Cell Growth Peptide Metabolic Process Amino Acid Transport	Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Morphogenesis Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Auditory Receptor Cell Development Inner Ear Receptor Stereocilium Organization Auditory Receptor Cell Differentiation Detection Of Mechanical Stimulus Involved In Sensory Perception Hair Cell Differentiation Inner Ear Receptor Cell Development Detection Of Mechanical Stimulus Inner Ear Receptor Cell Differentiation
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