NADK and NUDT18

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		NADK	NUDT18
Description		NAD kinase	nudix hydrolase 18
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GO Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	Nucleotide Binding NAD+ Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding	Protein Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity 8-oxo-dGDP Phosphatase Activity 8-oxo-GDP Phosphatase Activity 8-hydroxy-dADP Phosphatase Activity Metal Ion Binding
	Biological Process	NADP+ Biosynthetic Process Phosphorylation NAD+ Metabolic Process Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus ATP Metabolic Process	Nucleotide Metabolic Process DADP Catabolic Process DGDP Catabolic Process GDP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Nicotinate metabolism
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Body mass index ( 26426971 28892062) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Multiple sclerosis ( 31604244) Pulse pressure ( 28135244) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 28135244 30578418)
Interacting Genes		10 interacting genes: CRY2 EEF1G FAM124B GLRX3 GRB2 LNX1 NUDT18 SDCBP SRPK2 YWHAQ	34 interacting genes: APIP CAVIN2 COIL CUTC DCTD DHPS DUT EVI5L GLUL GNMT GSE1 HSD17B14 KCTD13 KCTD17 KHDRBS3 KRT15 KRTAP4-12 KXD1 NADK NAT9 NT5C2 PAICS PCBD1 PSME3 RAB3IL1 RABAC1 RAD54B RWDD1 TARBP2 TERF2IP TIFA TRAF2 TRIM37 ZBED1
Entrez ID		65220	79873
HPRD ID		16907	07992
Ensembl ID		ENSG00000008130	ENSG00000275074
Uniprot IDs		A0A0A0MR98 O95544	Q6ZVK8
PDB IDs		3PFN 8KGC 9CR3 9CR4 9CRA	3GG6 4HVY
Enriched GO Terms of Interacting Partners?		Photoreactive Repair Blue Light Signaling Pathway DNA (6-4) Photolyase Activity Deoxyribodipyrimidine Photo-lyase Activity Blue Light Photoreceptor Activity Guanyl-nucleotide Exchange Factor Adaptor Activity Intracellular Signaling Cassette Small GTPase-mediated Signal Transduction Grb2-EGFR Complex Ras Protein Signal Transduction Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex 14-3-3 Protein Binding 8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Negative Regulation Of Transport Cry-Per Complex 8-oxo-dGDP Phosphatase Activity Identical Protein Binding Intracellular Signal Transduction Negative Regulation Of Glucocorticoid Secretion Cytosol Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Nuclear Speck Organization Regulation Of Sodium-dependent Phosphate Transport	Identical Protein Binding DUMP Biosynthetic Process DTMP Biosynthetic Process Pyrimidine Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Metabolic Process Negative Regulation Of Defense Response To Virus By Host Protein Complex Oligomerization Protein Homooligomerization Pyrimidine Deoxyribonucleotide Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Deoxyribonucleotide Metabolic Process Cytosol Nucleoside Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Protein Binding Amino Acid Biosynthetic Process L-amino Acid Metabolic Process Small Molecule Metabolic Process Deoxyribonucleotide Biosynthetic Process 2'-deoxyribonucleotide Biosynthetic Process Methionine Metabolic Process Negative Regulation Of Defense Response To Virus Alpha-amino Acid Metabolic Process Protein-containing Complex Assembly IMP Metabolic Process Nucleotide Biosynthetic Process Purine Nucleobase Metabolic Process Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Nucleotide Metabolic Process Purine Nucleoside Metabolic Process Pyrimidine Nucleotide Biosynthetic Process Deoxyhypusine Synthase Activity Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process DUTP Catabolic Process DUTP Diphosphatase Activity Amino Acid Metabolic Process Intracellular Ammonium Homeostasis Tumor Necrosis Factor Receptor Binding Regulation Of SiRNA Processing Protein-containing Complex Organization TORC2 Complex Disassembly Protein Autosumoylation Phosphoribosylaminoimidazolesuccinocarboxamide Synthase Activity GMP Metabolic Process Phosphoribosylaminoimidazole Carboxylase Activity Nucleoside Phosphotransferase Activity GMP Catabolic Process To Guanine Tubulin N-terminal-methionine Acetyltransferase Activity
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