NADK

Gene Name		NAD kinase
Image
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	NAD+ Kinase Activity ATP Binding Metal Ion Binding
	Biological Process	NADP Biosynthetic Process Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Phosphorylation NAD Metabolic Process Small Molecule Metabolic Process ATP Metabolic Process
Pathways		Metabolism of vitamins and cofactors Defective GIF causes intrinsic factor deficiency Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Nicotinate metabolism Defects in vitamin and cofactor metabolism Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: EEF1G GLRX3 GRB2 LNX1 NUDT18 SDCBP YWHAQ
Entrez ID		65220
HPRD ID		16907
Ensembl ID		ENSG00000008130
Uniprot IDs		O95544 Q6PJ22
PDB IDs		3PFN
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Organelle Organization GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process Small GTPase Mediated Signal Transduction Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Ras Protein Signal Transduction Regulation Of Organelle Organization Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Negative Regulation Of Cardiac Muscle Hypertrophy Branching Involved In Labyrinthine Layer Morphogenesis Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Deoxyribonucleoside Diphosphate Metabolic Process Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Cellular Component Biogenesis Substrate-dependent Cell Migration, Cell Extension Purine Ribonucleoside Catabolic Process Positive Regulation Of Signal Transduction Deoxyribose Phosphate Catabolic Process Axon Guidance Protein Targeting Protein Oligomerization Labyrinthine Layer Morphogenesis Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Tagcloud ?		cytoskeleton dataset deposited dysregulation exerts expand heterodimeric http identifier inositol inpp5d mapkapk2 nonreceptor org pertaining phosphatases phosphoproteome phosphoproteomic polyphosphate proteomecentral proteomexchange ptpn12 pxd000984 reorganization ripk1 silac threonine tnfrsf