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HPS6 and MNAT1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
HPS6
MNAT1
Gene Name
Hermansky-Pudlak syndrome 6
MNAT CDK-activating kinase assembly factor 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Membrane
BLOC-2 Complex
Early Endosome Membrane
Nucleoplasm
Holo TFIIH Complex
Cytoplasm
Molecular Function
Rab GTPase Binding
GTP-dependent Protein Binding
Protein Binding
DNA-dependent ATPase Activity
Zinc Ion Binding
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Protein N-terminus Binding
Biological Process
Organelle Organization
Blood Coagulation
Melanocyte Differentiation
Protein Localization To Membrane
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Nucleotide-excision Repair, DNA Damage Removal
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Protein Complex Assembly
Protein Phosphorylation
Adult Heart Development
Cell Proliferation
Gene Expression
Viral Process
Ventricular System Development
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Apoptotic Process
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Viral Transcription
Response To Calcium Ion
Pathways
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Tat-mediated elongation of the HIV-1 transcript
Cyclin E associated events during G1/S transition
Formation of transcription-coupled NER (TC-NER) repair complex
Dual incision reaction in TC-NER
NoRC negatively regulates rRNA expression
G1/S Transition
Mitotic G1-G1/S phases
S Phase
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Global Genomic NER (GG-NER)
RNA Polymerase II Transcription Initiation And Promoter Clearance
Cyclin A:Cdk2-associated events at S phase entry
Mitotic G2-G2/M phases
Transcription of the HIV genome
Nucleotide Excision Repair
RNA Polymerase II Transcription
RNA Polymerase I Transcription Initiation
HIV Infection
RNA Polymerase I Promoter Clearance
Formation of the Early Elongation Complex
G2/M Transition
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Cyclin A/B1 associated events during G2/M transition
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Dual incision reaction in GG-NER
RNA Polymerase I Transcription
mRNA Capping
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
G1 Phase
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Cell Cycle, Mitotic
Cyclin D associated events in G1
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of incision complex in GG-NER
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Protein-Protein Interactions
9 interactors:
CREB1
EP300
HPS5
KIAA0020
MARK4
MNAT1
OSGEP
PIK3CB
TTC19
42 interactors:
BRCA1
CCNH
CDK7
COPS6
CTD
DMAP1
E2F1
EEF1A1
ERCC3
ESR1
GTF2E2
HPS6
LRIF1
MBP
MCM7
MDM4
MKRN3
MTA1
NGFRAP1
NKX3-1
POLR2A
POU2F1
POU2F2
POU5F1
RB1
RBM48
RNF32
RNF41
RNF7
SUPT5H
TP53
TRIM17
TRIM2
TRIM21
TRIM26
TRIM31
TRIM34
TRIM39
TRIM5
TRIM9
TRIML1
USP2
Entrez ID
79803
4331
HPRD ID
08471
04042
Ensembl ID
ENSG00000166189
ENSG00000020426
Uniprot IDs
Q86YV9
P51948
PDB IDs
1G25
Enriched GO Terms of Interacting Partners
?
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Positive Regulation Of Viral Transcription
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Cell Cycle Process
Histone H2B Acetylation
Protein Stabilization
Posttranscriptional Regulation Of Gene Expression
Threonylcarbamoyladenosine Biosynthetic Process
Viral Process
Cell Cycle
Regulation Of Body Fluid Levels
Phosphatidylinositol-mediated Signaling
N-terminal Peptidyl-lysine Acetylation
Regulation Of Protein Stability
Notch Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Regulation Of Viral Process
G1/S Transition Of Mitotic Cell Cycle
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Mitotic Cell Cycle Process
Circadian Rhythm
Threonylcarbamoyladenosine Metabolic Process
Regulation Of Tubulin Deacetylation
Cellular Response To Fibroblast Growth Factor Stimulus
Mitotic Cell Cycle
Response To Fibroblast Growth Factor
Neurotrophin TRK Receptor Signaling Pathway
Innate Immune Response
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Organelle Organization
Phosphorylation
Negative Regulation Of Transcription By Competitive Promoter Binding
Lung Development
Positive Regulation By Host Of Viral Transcription
Embryonic Cleavage
Mitochondrial Respiratory Chain Complex III Assembly
Respiratory Tube Development
Regulation Of Cellular Protein Metabolic Process
Response To Hormone
Fc Receptor Signaling Pathway
N-terminal Protein Amino Acid Acetylation
Response To Stress
Regulation Of Clathrin-mediated Endocytosis
Lung Saccule Development
Regulation Of Transcription, DNA-templated
Regulation Of Viral Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Viral Transcription
Protein Ubiquitination
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Protein Modification By Small Protein Conjugation
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Positive Regulation Of Viral Process
7-methylguanosine RNA Capping
Transcription, DNA-templated
DNA-templated Transcription, Elongation
Regulation Of Metabolic Process
RNA Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Response To Stress
Positive Regulation Of Viral Transcription
Viral Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of Viral Entry Into Host Cell
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To DNA Damage Stimulus
Regulation Of Viral Release From Host Cell
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of Cell Cycle
Macromolecule Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Response To Stimulus
Cellular Response To Stress
Nucleotide-excision Repair
Androgen Receptor Signaling Pathway
RNA Metabolic Process
Cellular Protein Modification Process
Transcription-coupled Nucleotide-excision Repair
Tagcloud
?
affymetrix
anthracycline
anthracyclines
atm
bc
bimodal
bub1
damaging
enable
fan1
fanci
fashion
impair
msh2
msh6
mtmr15
parp2
pcna
pms2
polq
recql4
regimens
residual
rpa3
sensitizing
survive
taxane
top2a
ube2v2
Tagcloud (Difference)
?
affymetrix
anthracycline
anthracyclines
atm
bc
bimodal
bub1
damaging
enable
fan1
fanci
fashion
impair
msh2
msh6
mtmr15
parp2
pcna
pms2
polq
recql4
regimens
residual
rpa3
sensitizing
survive
taxane
top2a
ube2v2
Tagcloud (Intersection)
?