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HPS6 and KIAA0020
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
HPS6
KIAA0020
Gene Name
Hermansky-Pudlak syndrome 6
KIAA0020
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Membrane
BLOC-2 Complex
Early Endosome Membrane
Nucleolus
Endoplasmic Reticulum
Molecular Function
Rab GTPase Binding
GTP-dependent Protein Binding
MRNA Binding
Poly(A) RNA Binding
Biological Process
Organelle Organization
Blood Coagulation
Melanocyte Differentiation
Protein Localization To Membrane
Regulation Of Translation
Pathways
Drugs
Diseases
GWAS
Blood trace element (Se levels) (
23720494
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
9 interactors:
CREB1
EP300
HPS5
KIAA0020
MARK4
MNAT1
OSGEP
PIK3CB
TTC19
2 interactors:
CALM1
HPS6
Entrez ID
79803
9933
HPRD ID
08471
08822
Ensembl ID
ENSG00000166189
ENSG00000080608
Uniprot IDs
Q86YV9
Q15397
PDB IDs
Enriched GO Terms of Interacting Partners
?
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Positive Regulation Of Viral Transcription
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Cell Cycle Process
Histone H2B Acetylation
Protein Stabilization
Posttranscriptional Regulation Of Gene Expression
Threonylcarbamoyladenosine Biosynthetic Process
Viral Process
Cell Cycle
Regulation Of Body Fluid Levels
Phosphatidylinositol-mediated Signaling
N-terminal Peptidyl-lysine Acetylation
Regulation Of Protein Stability
Notch Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Regulation Of Viral Process
G1/S Transition Of Mitotic Cell Cycle
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Mitotic Cell Cycle Process
Circadian Rhythm
Threonylcarbamoyladenosine Metabolic Process
Regulation Of Tubulin Deacetylation
Cellular Response To Fibroblast Growth Factor Stimulus
Mitotic Cell Cycle
Response To Fibroblast Growth Factor
Neurotrophin TRK Receptor Signaling Pathway
Innate Immune Response
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Organelle Organization
Phosphorylation
Negative Regulation Of Transcription By Competitive Promoter Binding
Lung Development
Positive Regulation By Host Of Viral Transcription
Embryonic Cleavage
Mitochondrial Respiratory Chain Complex III Assembly
Respiratory Tube Development
Regulation Of Cellular Protein Metabolic Process
Response To Hormone
Fc Receptor Signaling Pathway
N-terminal Protein Amino Acid Acetylation
Response To Stress
Regulation Of Clathrin-mediated Endocytosis
Lung Saccule Development
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Blood Coagulation
Hemostasis
Regulation Of High Voltage-gated Calcium Channel Activity
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Body Fluid Levels
Wound Healing
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Response To Wounding
Detection Of Calcium Ion
Regulation Of Cell Communication By Electrical Coupling
Positive Regulation Of Phosphoprotein Phosphatase Activity
Positive Regulation Of Peptidyl-threonine Phosphorylation
Positive Regulation Of Protein Autophosphorylation
Membrane Organization
Positive Regulation Of Nitric-oxide Synthase Activity
Glycogen Catabolic Process
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Negative Regulation Of Peptidyl-threonine Phosphorylation
Regulation Of Voltage-gated Calcium Channel Activity
Positive Regulation Of Protein Dephosphorylation
Negative Regulation Of Cation Channel Activity
Polysaccharide Catabolic Process
Positive Regulation Of Monooxygenase Activity
Positive Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Regulation Of Rhodopsin Mediated Signaling Pathway
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Activation Of Adenylate Cyclase Activity
Nitric Oxide Metabolic Process
Regulation Of Protein Autophosphorylation
Reactive Nitrogen Species Metabolic Process
Rhodopsin Mediated Signaling Pathway
Cellular Carbohydrate Catabolic Process
Positive Regulation Of Phosphatase Activity
Response To Corticosterone
Positive Regulation Of Cation Channel Activity
Response To Amphetamine
Positive Regulation Of Adenylate Cyclase Activity
Regulation Of Phosphoprotein Phosphatase Activity
Regulation Of Nitric-oxide Synthase Activity
Response To Mineralocorticoid
Substantia Nigra Development
Positive Regulation Of Oxidoreductase Activity
Melanocyte Differentiation
Negative Regulation Of Transporter Activity
Negative Regulation Of Calcium Ion Transport
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Tagcloud (Intersection)
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