HPS6 and HPS5

Number of citations of the paper that reports this interaction (PubMedID 12548288)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		HPS6	HPS5
Description		HPS6 biogenesis of lysosomal organelles complex 2 subunit 3	HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Endosome Early Endosome Endoplasmic Reticulum Cytosol Membrane BLOC-2 Complex Early Endosome Membrane	Cytoplasm Early Endosome Cytosol BLOC-2 Complex
	Molecular Function	Protein Binding GTP-dependent Protein Binding Small GTPase Binding	Protein Binding
	Biological Process	Lipid Metabolic Process Blood Coagulation Protein Secretion Lysosome Localization Pigmentation Lipid Homeostasis Platelet Dense Granule Organization Protein Localization To Membrane Melanosome Assembly	Blood Coagulation Pigmentation Developmental Pigmentation Platelet Dense Granule Organization Melanosome Assembly
Pathways
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)	Hermansky-Pudlak syndrome (HPS)
GWAS		Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)	Adiponectin levels ( 33562295) Amyloid A serum levels ( 21124955) Metabolic traits ( 21886157) Serum metabolite levels ( 23093944) Survival in pancreatic cancer ( 28470677) Triglyceride levels ( 32203549)
Interacting Genes		11 interacting genes: CREB1 EP300 HPS5 MARK4 MNAT1 OSGEP PIK3CB PUM3 SUMO2 TTC19 UBC	2 interacting genes: HPS6 ITGA3
Entrez ID		79803	11234
HPRD ID		08471	07395
Ensembl ID		ENSG00000166189	ENSG00000110756
Uniprot IDs		Q86YV9	Q9UPZ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Tag Activity Nucleoplasm Chemotaxis To Arachidonate Transcription Coactivator Binding Tau Protein Binding Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Midbody Positive Regulation Of Cardiac Muscle Tissue Development Positive Regulation Of Transforming Growth Factor Beta3 Production Secretory Granule Organization Locomotion Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity BLOC-2 Complex TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity	Growth Cone Filopodium Integrin Alpha3-beta1 Complex BLOC-2 Complex
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